Tag: tumor-associated macrophages

A mannose-decorated zinc metal-organic framework nanovaccine delivering the tumor antigen CLDN6 reprograms immunosuppressive macrophages in lung tumors into antigen-presenting cells ...

A pan-cancer single-cell epigenetic study reveals that tumor-supportive macrophages arise through distinct enhancer-driven trajectories in which releasing paused RNA polymerase ...

New research shows that blocking the TREM2 receptor reprograms HER2-targeted CAR macrophages from suppressive to inflammatory, tumor-engulfing cells in breast ...

A new study shows that exosomes released by tumor-associated macrophages carry PD-L1 that reprograms the metabolism of CD8-positive T cells, ...

Researchers have developed the first immunoPET tracer targeting human CD68, a synthetic zirconium-89-labeled antibody fragment that visualized macrophages in mouse ...

A new review in the Journal of Ovarian Research details how chronic inflammatory signaling pathways drive ovarian cancer progression and ...

New research shows that the stromal protein RAMP3 drives macrophage-mediated immune exclusion in breast cancer and undermines PD-1 blockade, suggesting ...

New research shows that ischemic stroke reprograms tumor-associated astrocytes with reduced calcium signaling, which recruit macrophages and accelerate glioma invasion.

A bacterial protein called LukS-PV reprograms immunosuppressive macrophages in liver cancer by targeting the human C5aR1 receptor, restoring CD8-positive T-cell ...

A new review argues that the immune checkpoint VISTA acts as a myeloid-centered axis in tumors, offering a route past ...