New Template System Predicts How Two Key Enzymes Metabolize and Inhibit Chemicals
Researchers constructed a fused-grid template model of the human enzyme CYP1B1 and, paired with an existing CYP1A1 template, verified more ...
Tag: toxicology
Mango Waste Gets a Second Life in Drugs and Cosmetics, Review Finds
A new review finds that mango peel and seed, which make up 35 to 60 percent of processing waste, are ...
Carbon Monoxide Clears Slower Than Expected: Oxygen Therapy Half-Life Falters Over Time
A retrospective study of 159 patients finds that carboxyhemoglobin elimination during normobaric oxygen therapy slows markedly after the first two ...
Europe’s Research Infrastructures Push to Untangle the Microplastics Mess
A new perspective argues that coordinating European research infrastructures is the key to overcoming fragmentation in micro- and nanoplastic research.
Mouse Bone Marrow Test Finds No Genotoxic Signs for Solar Foods’ Solein Protein Powder
A GLP-compliant mouse micronucleus test found no increases in micronucleated bone marrow cells after oral dosing of Solein, the bacterial ...
Ten Years of Bee Sting Records Reveal Envenomation Patterns in French Guiana
A ten-year retrospective study of 143 bee sting patients at Cayenne Hospital in French Guiana found that 40% showed systemic ...
FDA, EMA and NMPA differ in how they assess radiopharmaceuticals, review finds
A review published in EJNMMI Radiopharmacy and Chemistry compares how the FDA, EMA and NMPA evaluate radiopharmaceuticals before clinical use ...
Vitamin C Shields Rat Brains, Hearts and Livers from Ivermectin and Hydroxychloroquine Damage in Experimental Study
A rat study found that three weeks of ivermectin or hydroxychloroquine dosing caused oxidative stress, tissue damage and apoptosis markers ...
Experimental Antifungal ISFP10 Shows Potent Candida Activity and Safe Profile in Mice
The experimental compound ISFP10, which selectively inhibits a fungal-specific cell wall enzyme, showed potent activity against Candida strains in vitro ...
Biological fingerprints beat chemical structure in predicting drug-induced steatosis
Machine-learning models built from protein-target and pathway fingerprints outperform chemical structure models in predicting drug-induced fatty liver, a new study ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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