Observational cohort finds uncertain fetal risk after first-trimester JAK inhibitor exposure
A German Embryotox observational cohort found two major congenital anomalies among 32 live births after first-trimester JAK inhibitor exposure, but ...
Tag: tofacitinib
Tofacitinib lowers blood pressure and alters vascular tone in 28-day mouse study
A 28-day animal study reports dose-dependent blood pressure reductions, decreased CPK-MB, increased basilar artery tone, and nonlinear mortality in tofacitinib-treated ...
Silent Liver Enzymes in a Nine-Year-Old Boy Led Doctors to a Surprising Autoimmune Diagnosis
A new case report describes how two years of unexplained, mildly elevated liver enzymes in a nine-year-old boy ultimately pointed ...
When Steroids Fail: Drug Combo Rescues Cancer Patient From Deadly Immunotherapy Heart Complication
A case report from Zhongshan Hospital describes how early second-line immunosuppression with tofacitinib and mycophenolate mofetil rescued a 77-year-old woman ...
One Dose of a New Immunotherapy Combo Triggered Four Organ Crises in a Lung Cancer Patient
A single cycle of atezolizumab plus tiragolumab triggered simultaneous myocarditis, hepatitis, thrombocytopenia, and dermatomyositis in a lung cancer patient, whose ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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