Ribosomal Protein RPL28 Emerges as a Driver and Prognostic Marker in Kidney Cancer
New research shows that the ribosomal protein RPL28 is overexpressed in clear cell renal cell carcinoma, where it independently predicts ...
Tag: TCGA
Cancer Gene Duo Reveals Why Head and Neck Tumors Shrug Off Cisplatin
New research links the SERPINE1–CA9 gene axis to both aggressive growth and cisplatin resistance in head and neck squamous cell ...
One Tiny RNA, Many Cancers: Meta-Analysis Confirms miR-221 as a Pan-Cancer Killer Signal
A pan-cancer systematic review and meta-analysis links elevated microRNA-221 to significantly worse survival across multiple tumor types and maps its ...
Lab-Grown Brain Tumor Organoids Build Their Own Blood Vessels and Scaffolding
Researchers have grown glioblastoma organoids without any exogenous scaffold, allowing tumor stem cells to autonomously assemble neurovascular-like structures and extracellular ...
PTPN6 Gene Emerges as Potential Prognostic Marker in Bladder Cancer
A new bioinformatics study links PTPN6 overexpression and promoter hypomethylation to overall survival in bladder cancer, positioning the gene as ...
AI Reads Three Layers of Breast Cancer Biology at Once to Sharpen Subtype Diagnosis
A new hierarchical cross-attention framework integrates mRNA, microRNA, and DNA methylation data to classify breast cancer subtypes more accurately and ...
Three-Gene Signature Predicts Survival and Platinum Drug Response in Liver Cancer
Researchers at Sun Yat-Sen University have developed a three-gene signature based on platinum resistance biology that predicts overall survival and ...
Cancer Cells Rewire Their Fuel Supply When This Growth Signal Switches On
New research reveals that HGF/c-MET signaling reprograms glutamine metabolism in MET-amplified head and neck cancer cells through ERK-dependent induction of ...
Immune Checkpoint BTLA Emerges as Surprising Prognostic Marker in Ovarian Cancer
A multi-omics study identifies the immune checkpoint molecule BTLA as significantly upregulated in ovarian cancer and associated with favorable overall ...
Auditable AI Framework Ranks Class I HDAC Inhibitors for Cancer Reversal
A leakage-aware, auditable computational framework trained on LINCS L1000 signatures identifies class I HDAC inhibitors, led by Mocetinostat, as top ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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