Tag: targeted cancer therapy

A new review argues that deubiquitinase enzymes within the ubiquitin-proteasome system offer promising therapeutic angles against KRAS-driven cancers that resist ...

A multimodal proteomics study shows that ATP-competitive kinase inhibitors displace autoinhibitory domains, driving unexpected non-catalytic functions relevant to drug development.

Researchers have engineered EB-18, a phosphonium-substituted derivative of the classic chemotherapy drug 5-fluorouracil that outperforms 5-FU and standard agents in ...

Two landmark New England Journal of Medicine studies show the pan-RAS inhibitor daraxonrasib nearly doubles survival in previously treated metastatic ...

A new review in Medical Oncology argues that simultaneously targeting copper-triggered cuproptosis and iron-dependent ferroptosis could open a powerful two-front ...

A new review details how tunable crystalline MOFs are advancing both water purification and precision medicine.

A synthetic compound derived from a family of molecules first described in the nineteenth century is emerging as a surprising ...

In a finding that could reshape the treatment landscape for one of the most difficult scenarios in breast cancer care, ...

Scientists in Italy and China have engineered a designer molecule that slips into cervical cancer cells and disarms the engine ...

Scientists have identified a little-known signalling protein that appears to operate as a hidden engine of colorectal cancer, quietly fuelling ...