CISD2 knockdown suppresses gastric cancer and triggers ferroptosis
Knocking down CISD2 suppresses gastric cancer cell growth and induces ferroptosis through inhibition of the mTOR/SREBF1/SCD1 axis and GPX4 downregulation, ...
Tag: SREBF1
Blood lipid–linked DNA methylation patterns replicate in Korean adults and tie to epigenetic aging
An epigenome-wide study of 1,527 Korean adults confirms core lipid–methylation loci and links ABCG1 methylation to the association between accelerated ...
Scientists Link a DNA-Building Enzyme to Fat Rewiring and Chemotherapy Failure in Pancreatic Cancer
A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...
Silencing a Fat-Making Master Switch Pushes Pancreatic Cancer Cells Toward Self-Destruction
New research links elevated SREBF1 expression to lipid metabolism signatures in pancreatic cancer and shows that silencing the gene triggers ...
One Obesity Gene Variant Rewires Nearly 100 Genes in Fat Cells, Study Finds
Researchers combined single nucleus RNA-sequencing with GWAS and UK Biobank data to show that an obesity-linked variant in SREBF1 allele-specifically ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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