Light-Patterned DNA Tags Give Single-Cell Sequencing a Sense of Place
A new light-based barcoding technique called scSTAMP-seq stamps spatial coordinates onto individual cells using photocleavable DNA tags, enabling joint transcriptomic ...
Tag: single-cell sequencing
New AI framework DePass cleans and merges multi-omics data across cells and tissues
Researchers have developed DePass, a dual-enhanced graph learning framework that iteratively denoises and integrates paired multi-omics data across single-cell and ...
Grilled and Smoked Food Carcinogen Benzo[a]pyrene Linked to Prostate Cancer Through Four Key Genes
A network toxicology and machine learning study identifies four genes through which the environmental carcinogen benzopyrene may drive prostate cancer ...
Mitochondrial DNA Mosaics May Serve as a Molecular Clock of Human Aging
A new review argues that clonally expanded mitochondrial DNA mutations accumulate in a tissue-specific, biphasic pattern that can be read ...
How Microglial Metabolism and Mitochondria Drive Brain Damage After Stroke
A new review integrates mitochondrial quality control, metabolic reprogramming, and NLRP3 inflammasome activation into a single framework explaining how microglia ...
Personalized Neoantigen Vaccine Turns a Patient’s Immune System Into a TCR Discovery Engine
A personalized dendritic cell neoantigen vaccine given to an ovarian cancer patient enabled Swiss researchers to track expanding T-cell clonotypes ...
Brain Mosaicism Links Development, Ageing and Neurodegeneration
A new review argues that somatic mosaicism is a pervasive feature of the human brain that links development, ageing and ...
Scientists Map How Tumours Push Immune Cells Into Exhaustion
A review in Experimental & Molecular Medicine examines how chronic antigen exposure and a hostile tumour microenvironment reprogram T cells ...
Scientists Flip the Drug Discovery Pipeline to Put Human Biology First in Cardiovascular Research
A new perspective argues that cardiovascular discovery should begin with integrated human multi-omics data rather than animal models, reversing the ...
Transfer Learning Reconstructs the Signaling Histories of Single Cells
A new computational framework called IRIS uses perturbation screening data and transfer learning to reconstruct the signaling states and histories ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!