Tag: single-cell RNA sequencing in cancer

Sequencing of 11 colorectal cancer patients shows peritoneal metastases often arise early, polyclonally, and through metastasis-to-metastasis seeding.

Single-cell and multi-omics analyses of hepatocellular carcinoma point to IL-1β-positive macrophages and IL-1R1-positive inflammatory fibroblasts as putative drivers of a ...

SLC5A12 marked an invasive HNSCC state, and experimental knockdown reduced tumor-cell behaviors and xenograft growth in preclinical models.

Single-cell and bulk transcriptomic analyses linked TIMP1 to anoikis resistance in esophageal squamous cell carcinoma, while cell and mouse experiments ...

Gastric cancer remains one of the world's most lethal malignancies, and a new study has added an unexpected twist to ...

Osteosarcoma has long frustrated oncologists. It is the most common primary malignant bone tumor, striking hardest in adolescents, and while ...

Single-cell sequencing, organoids, and xenografts reveal that the securin-encoding gene PTTG1 reprograms the G2/M checkpoint to drive the stepwise progression ...

By integrating bulk and single-cell RNA sequencing with machine learning, researchers in China have identified a nine-gene macrophage signature that ...

A new study links the hepatitis B virus X protein to tumor-derived MIF signaling that drives CD8-positive T cell exhaustion ...

In a groundbreaking study published in Nature, researchers at The University of Texas MD Anderson Cancer Center have delivered unprecedented ...