Sirtuin 1 emerges as the molecular switch linking cellular senescence to heart failure
A new review argues that the longevity enzyme sirtuin 1 sits at the molecular crossroads between cellular senescence and heart ...
Tag: SGLT2 inhibitors
Diabetes Drugs Show Promise for Stroke Survivors, but Guidelines Lag Behind
Two drug classes born as diabetes therapies are quietly reshaping cardiovascular medicine, and a group of European stroke specialists argues ...
Control Theory Offers a New Mathematical Map for Safer Aging Drug Discovery
A new control theory framework published in Aging redefines aging as a progressive loss of safe controllability and proposes safety-first ...
Diabetes drug reshapes pancreatic insulin response in horses with metabolic disease
A randomized clinical trial shows that four weeks of canagliflozin treatment significantly reduces pancreatic beta-cell responsiveness to glucose in insulin-dysregulated ...
Why Diabetes Makes Urinary Tract Infections More Frequent, Severe, and Hard to Treat
A new review explains why diabetes doubles to quadruples urinary tract infection risk, how high blood sugar and bacterial virulence ...
The Hidden Gap Between Percentages and Patients: Why Trial Headlines Mislead Doctors
A new viewpoint in eClinicalMedicine argues that cardiorenal trials should routinely report absolute risk reduction and number needed to treat ...
Machine Learning Reveals Three Diabetes Patient Types Shaping Heart and Kidney Drug Choices
A real-world study of 9000 patients with type 2 diabetes in China used cluster analysis to identify three clinical phenotypes ...
Four Years of Pandemic Diabetes Care Reveal a Lasting Shift Toward Virtual Medicine
A four-year cohort study found that diabetes care during the COVID-19 pandemic shifted durably toward telemedicine and intensified drug therapy ...
Diabetes Drugs May Ease Pulmonary Hypertension by Taming Activin A Signaling
A new study links SGLT2 inhibitor therapy with reduced circulating activin A, improved right-heart function, and modulation of BMP/activin signaling ...
Kidney Damage, Not Blood Sugar Alone, Drives Hospital Stays in Oldest Diabetes Patients
A Swedish population-based study of adults aged 75 and older with type 2 diabetes finds that advanced chronic kidney disease ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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