Anesthesia and Surgery Rewire the Alzheimer’s Brain Differently, Mouse Study Suggests
A new exploratory RNA sequencing study finds that the hippocampal response to anesthesia and surgery is directionally inverted in 5xFAD ...
Tag: RNA sequencing
Scientists Engineer Shear-Resistant Prostate Cancer Cells and Uncover a Survival Gene
Researchers have created the first stable prostate cancer cell lines resistant to blood-flow-level shear stress and identified the calcium-buffering gene ...
Gut Bacterium Found Migrating to the Liver May Drive Autoimmune Bile Duct Disease
Researchers report that Klebsiella pneumoniae enriched in the guts of primary biliary cholangitis patients can translocate to the liver and ...
Fifteen Cotton Pest Transcriptomes Reveal Shared Gene Targets for Next-Generation Pest Control
A comparative transcriptomic study of fifteen cotton pest species across four insect orders identifies conserved genes such as vitellogenin and ...
Smoke Tree Flavonoids Rewrite Gene Activity in Leukemia Cells, Study Finds
A transcriptomic study shows that three flavonoids from smoke tree heartwood suppress leukemia cell growth by shutting down RNA processing ...
Female Mice Pay a Heavier Price: Sex Hormones Speed Retinal Degeneration
New research shows that female mice lacking the protein quality-control gene Herc3 suffer faster retinal thinning, greater inflammatory activation, and ...
Deep Learning Tool Reads RNA Tails Straight From Nanopore Signals
A new deep learning framework called PolyAnalysis estimates RNA poly(A) tail lengths directly from raw nanopore sequencing signals and profiles ...
Rumen Fluke Parasite Reveals Its Molecular Playbook Across Life Stages
A new transcriptomic study of the rumen fluke Calicophoron daubneyi reveals that its eggs, rediae and cercariae each deploy distinct ...
Platelet RNA Reveals Hidden Molecular Fingerprints of Glioblastoma in a Simple Blood Test
A re-analysis of platelet RNA sequencing data from glioblastoma patients identifies dysregulated pathways and a 103-gene blood-based signature that distinguishes ...
Virtual Screening Yields a Potent New MAPKAPK2 Inhibitor Against Pancreatic Cancer
Researchers used structure-based virtual screening of roughly 280,000 compounds to discover compound 77501, a novel and selective MAPKAPK2 inhibitor that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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