Methods for Handling Non-Compliance in Randomized Trials
A new methodological assessment evaluates how different statistical models and summary measures handle non-compliance in the experimental arm of randomized ...
Tag: restricted mean survival time
Evaluating Statistical Methods for Sequential Parallel Comparison Designs Under Non-Proportional Hazards
A systematic evaluation shows statistical test performance diverges under non-proportional hazards in sequential parallel comparison clinical trial designs.
New Estimator Targets Hypothetical Trial Effects When Time-to-Event Events Intervene
Researchers have developed a generalized Nelson–Aalen estimator that targets hypothetical estimands via the controlled direct effect when time-to-event intercurrent events ...
Leukemia and Lymphoma Patients Fare Similarly After Stem Cell Transplants, Study Finds
A 15-year retrospective study of 106 transplant patients shows that T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma yield broadly ...
Most Children with Life-Limiting Conditions Live for Years, Landmark Danish Study Finds
A nationwide Danish cohort study of more than 100,000 children and adolescents shows that most children diagnosed with life-limiting conditions ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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