Ravulizumab in Pregnancy Shows No New Safety Signals in Global Analysis
A global pharmacovigilance analysis of 354 pregnancies found no unexpected safety signals with the complement inhibitor ravulizumab, with outcomes consistent ...
Tag: Real-world evidence
Real-World Data Show Carfilzomib Regimens Deliver Strong Results in Multiple Myeloma
The final results of the German CARO study show that carfilzomib-based regimens achieve high adherence, trial-consistent effectiveness, and stable quality ...
One Pill, Two Drugs: How a Single-Tablet PAH Therapy Is Reshaping US Practice
A new real-world study of 144 US patients shows the first once-daily single-tablet macitentan/tadalafil combination for pulmonary arterial hypertension is ...
Widely Used Weight-Loss Drugs Linked to Sharply Lower Heart Risks in Sleep Apnea Patients
A large real-world study finds that GLP-1 receptor agonists are associated with significantly reduced risks of heart failure, pulmonary hypertension, ...
Two-Thirds of Eligible Lung Cancer Patients Miss Guideline-Backed Infection Shield, French Data Show
A nationwide analysis of French hospital cohorts finds that only about two-thirds of small-cell lung cancer patients eligible for G-CSF ...
After Natalizumab: Real-World Study Pits Two B-Cell Drugs Head to Head in Multiple Sclerosis
A retrospective real-world study from Milan's San Raffaele institute compares ocrelizumab and ofatumumab as successor therapies for multiple sclerosis patients ...
Statistician Wins FDA Funding to Quantify Record Linkage Uncertainty in Real-World Evidence
A George Mason statistician has received FDA funding to develop regulatory-grade frameworks that quantify how record linkage errors affect the ...
Real-World Data Show Trastuzumab Deruxtecan Extends Survival in HER2-Low Metastatic Breast Cancer
A real-world cohort of 126 Chinese patients shows trastuzumab deruxtecan delivers a median 9.1 months of progression-free survival in HER2-low ...
One in Five Lymphoma Patients on R-CHOP Suffers Febrile Neutropenia, Real-World Analysis Finds
A new systematic review finds that about one in five adults with diffuse large B-cell lymphoma develops febrile neutropenia during ...
Real-World Data Show Antibody-Drug Conjugate Still Works in Late-Stage Triple-Negative Breast Cancer
A multicenter Central European real-world study finds sacituzumab govitecan delivers meaningful survival benefit and manageable toxicity in heavily pretreated metastatic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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