Newer Lung Cancer Drug Alone Beats Older Combination Therapy in Real-World Study
A large real-world study in China found that third-generation EGFR inhibitor monotherapy extended progression-free survival in advanced EGFR-mutant lung cancer ...
Tag: Real-world evidence
Integrase Inhibitors Suppress HIV Faster but Bring Metabolic Trade-offs in Real-World Chinese Cohort
A province-wide cohort study of 7,474 treatment-naïve adults in Shandong, China finds INSTI-based initial HIV therapy outperforms NNRTI-based regimens on ...
Tildrakizumab Shows Sustained Real-World Benefit in Japanese Psoriasis Patients Over 52 Weeks
A 52-week Japanese observational study found that tildrakizumab sustained meaningful disease control in real-world psoriasis patients, with 60 percent achieving ...
Early CFTR Modulator Therapy Shows Real-World Benefits in Preschool Children with Cystic Fibrosis
A multicenter Italian study and an accompanying commentary provide real-world evidence that early lumacaftor/ivacaftor therapy improves CFTR function biomarkers and ...
Intravenous Esketamine Acts Faster, but Subcutaneous Route Matches Final Outcomes in Treatment-Resistant Depression
A multicenter Brazilian study finds intravenous esketamine produced faster antidepressant response in treatment-resistant depression, while a longer subcutaneous protocol achieved ...
Liraglutide Doses Below 3.0 mg Show Real-World Benefit, but Cost Blocks Half of Patients
A Taiwanese post-marketing surveillance study finds that nearly half of patients who failed to reach the approved 3.0 mg liraglutide ...
Mepolizumab Edges Out Dupilumab in Head-to-Head Real-World Asthma Biologic Showdown Among Older Medicare Patients
A large real-world study of Medicare beneficiaries found mepolizumab matched dupilumab for preventing asthma hospitalizations and significantly reduced exacerbation rates, ...
Hungary’s Decade of Data Reveals the Harsh Reality of Extensive-Stage Small Cell Lung Cancer
A nationwide analysis of 8,104 Hungarian patients treated from 2013 to 2022 shows median survival of just 9.3 months with ...
Diabetes Does Not Raise the Risk of Revision ACL Reconstruction, Large Real-World Study Finds
A study of nearly 74,000 patients across 53 healthcare organisations found that diabetes mellitus was not associated with an increased ...
Dual-Targeted Therapy Brings Remission to Half of Patients with Hardest-to-Treat Inflammatory Bowel Disease
A real-world study from Abu Dhabi found that pairing two advanced therapies with different mechanisms achieved combined clinical and biochemical ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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