Rare NF1-Linked Brain Tumors Show Partial Shrinkage on MEK Blocker Mirdametinib
A retrospective MD Anderson cohort of nine adults with NF1-associated high-grade glioma found partial radiographic responses in two patients treated ...
Tag: RAS/MAPK pathway
BabyMERIT Trial to Test Trametinib for Severe Infantile Hypertrophic Cardiomyopathy
The NIH-funded BabyMERIT trial will test trametinib in 25 infants with severe hypertrophic cardiomyopathy associated with Noonan syndrome and related ...
Landmark Meta-Analysis Maps the Hidden Psychiatric Burden of Neurofibromatosis Type 1
A new meta-analysis of fifty studies finds that people with neurofibromatosis type 1 face sharply elevated rates of ADHD, autism, ...
RASopathy Subtype Shapes Early Hypertrophic Cardiomyopathy Course, Study Finds
A new study in Pediatric Research is sharpening scientists’ understanding of why some patients with RASopathies develop severe, early-onset hypertrophic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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