Scarring Lungs Light Up on PET Scans, Hinting at How Deadly Pulmonary Fibrosis Will Become
New research links metabolic activity measured by FDG-PET/CT in scarred lung tissue to clinical severity and hints at faster disease ...
Tag: pulmonary fibrosis
Endothelial Angptl2 Emerges as Central Driver of Influenza-Linked Lung Fibrosis
New research identifies endothelial Angptl2 as a key molecular driver linking influenza-induced vascular injury to pulmonary fibrosis through EndMT and ...
Macrophage Exosomes Carry a MicroRNA That Drives Scarring in the Lung, Study Finds
Researchers report that M2 macrophage-derived exosomal miR-350-5p accelerates pulmonary fibrosis by suppressing Smad7 and amplifying TGF-beta signaling in lung fibroblasts ...
Nebulized Designer Exosomes Deliver Pirfenidone Directly to Fibrotic Lungs
Researchers engineered anti-FAP-targeted exosomes loaded with pirfenidone and showed that nebulized delivery outperforms intravenous injection in treating pulmonary fibrosis in ...
Tiny Cellular Bubbles May Drive and Heal Pulmonary Fibrosis
A new review details how extracellular vesicles and their microRNA cargo drive pulmonary fibrosis while also offering promising diagnostic biomarkers ...
RNA Tag METTL3 Drives Lung Scarring by Destabilizing a Key Fat-Droplet Protein
New research shows that the RNA methyltransferase METTL3 promotes lipid deposition and pulmonary fibrosis by destabilizing the messenger RNA of ...
Machine Learning Hunt Pinpoints Gene Linked to a Heart Drug’s Lung Damage
An integrated multiomics and machine learning study has identified SERPING1 as a leading candidate biomarker for amiodarone-induced pulmonary fibrosis, with ...
Scientists Discover PTCHD4 as a Novel Driver of Cellular Aging and Age-Related Disease
Researchers have identified the little-studied transmembrane protein PTCHD4 as a novel regulator of cellular senescence whose deletion extends lifespan and ...
Aerobic Glycolysis Emerges as a Key Driver of TGF-β-Induced EMT in Lung Cells
New research in Cell Death Discovery examines how aerobic glycolysis supports TGF-β-induced epithelial-to-mesenchymal transition in lung epithelial cells.
DCLK1 drives fibroblast activation and lung fibrosis via Smad3 binding
Idiopathic pulmonary fibrosis, a relentlessly progressive and fatal scarring disease of the lungs, has long frustrated clinicians with only two ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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