Macrophage Gene Signatures Predict Colorectal Cancer Prognosis, Machine Learning Study Finds
By integrating bulk and single-cell RNA sequencing with machine learning, researchers in China have identified a nine-gene macrophage signature that ...
Tag: prognostic signature
Common Cosmetic Preservative Methylparaben Linked to Breast Cancer Mechanisms in Landmark Computational Study
A new computational study links the common cosmetic preservative methylparaben to five key breast cancer signaling proteins and unveils a ...
RNA Modification and Cell Death Genes Point to New Prognostic Tool for Ovarian Cancer
Researchers built a machine learning gene signature combining RNA modification and programmed cell death biology that predicts survival and immunotherapy ...
RNA Chemical Tag ac4C Reveals Fibroblast Signal That Drives Colorectal Cancer Aggression
A comprehensive profiling study links the ac4C RNA modification to aggressive colorectal cancer and identifies CERCAM in cancer-associated fibroblasts as ...
Single-Cell Map Reveals Five Macrophage States Behind Chemotherapy Resistance in AML
Single-cell RNA sequencing of post-chemotherapy AML bone marrow has identified five macrophage polarization states whose abundance tracks with treatment response ...
Three-Gene Signature Predicts Survival and Platinum Drug Response in Liver Cancer
Researchers at Sun Yat-Sen University have developed a three-gene signature based on platinum resistance biology that predicts overall survival and ...
Tiny Cell Structures Called Migrasomes May Predict Gastric Cancer Outcomes
A new study links fibroblast-derived migrasome programs and the protein TSPAN4 to gastric cancer progression and builds a highly accurate ...
Four-Gene Signature Tied to Young Age Predicts Breast Cancer Recurrence Risk
A new study identifies a four-gene expression signature linked to young age that independently predicts recurrence risk in breast cancer.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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