Single-Cell Atlas of Glioma Reveals Astrocyte Gene TTYH1 as a Hidden Tumor Suppressor
An integrated single-cell and spatial multi-omics study of glioma identifies the astrocyte-associated gene TTYH1 as a tumor suppressor that impedes ...
Tag: prognostic biomarker
Two Proteins in Tiny Biopsies May Predict Survival in Pancreatic Cancer
A prospective Japanese study finds that combined high expression of PODXL and ITGB1 in preoperative EUS-FNAB biopsy specimens independently identifies ...
A Simple Brain Scan Ratio Predicts Survival in Cancer That Spreads to the Brain’s Linings
A large real-world cohort study confirms that the Evans index, a simple ratio measured on routine brain scans, independently predicts ...
RNA Chemical Tag Drives Endometrial Cancer Through a DNA Repair Protein, Study Finds
New research reveals that the RNA modification reader ALYREF drives endometrial cancer progression by stabilizing XRCC6 mRNA and activating Wnt/β-catenin ...
Ribosomal Protein RPL28 Emerges as a Driver and Prognostic Marker in Kidney Cancer
New research shows that the ribosomal protein RPL28 is overexpressed in clear cell renal cell carcinoma, where it independently predicts ...
Blood Group O Linked to Longer Survival in MGMT-Methylated Glioblastoma Patients
A retrospective study at University Hospital Bonn independently confirms that blood group O is associated with significantly longer progression-free and ...
AI Counts Tumor Buds in Colon Cancer Slides, Offering a New Prognostic Edge
A semi-supervised deep learning system called TBMNet accurately quantifies tumor budding in colorectal cancer slides and reveals molecularly distinct budding ...
PTPN6 Gene Emerges as Potential Prognostic Marker in Bladder Cancer
A new bioinformatics study links PTPN6 overexpression and promoter hypomethylation to overall survival in bladder cancer, positioning the gene as ...
Fourth-Generation CAR T Cells Targeting MUC1 Show Enhanced Power Against Breast Cancer
Researchers have developed fourth-generation CAR T cells targeting mucin 1 that show superior proliferation, reduced exhaustion, and enhanced tumor-killing activity ...
CBL Deletion in Stage II Melanoma: Why Statistics Matter Before Calling It a Prognostic Biomarker
A new correspondence in the British Journal of Cancer cautions that unadjusted statistical significance and sub-stage confounding must be resolved ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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