Lab-Grown Bone Marrow Models Reshape How Myeloma Is Studied
A new review maps how 3D bone marrow models, from spheroids to bioprinted and organ-on-chip systems, are being used to ...
Tag: Precision medicine
Pneumonia-driven ARDS emerges as biologically distinct syndrome demanding tailored care
A narrative review argues that pneumonia-driven ARDS is a biologically distinct, heterogeneous form of respiratory failure in which pathogen burden, ...
Metabolites Emerge as Signaling Hubs Driving Diabetic Kidney Disease
A new review reframes diabetic kidney disease as a network-level disease driven by metabolites acting as signaling mediators, biomarkers and ...
Sepsis is not one disease: how subphenotypes could reshape precision therapy
A narrative review argues that sepsis is a biologically heterogeneous syndrome whose reproducible subphenotypes may eventually guide targeted treatment, though ...
New roadmap outlines latest therapeutic progress for systemic sclerosis
A new narrative review in BMC Rheumatology summarises current best practice for managing systemic sclerosis, highlighting cellular therapies, multi-omics and ...
Recalibrating Polygenic Risk Scores to Local Data Sharpens Disease Risk Prediction
A new framework recalibrates published polygenic risk scores to local biobank data, improving risk prediction for coronary artery disease, breast ...
Light therapy in dentistry moves toward precision dosimetry, review argues
A narrative review argues that photobiomodulation's strongest evidence lies in oral mucositis prevention, while inconsistent dosimetry and reporting standards hold ...
Host Genomics Could Reshape How Doctors Diagnose Immune Disorders and Treat Infections
More than 30 experts outline how patients' germline genomes could improve infectious disease care, from detecting rare immune disorders early ...
Pneumonia may lead to sepsis through a failing immune boundary, researchers argue
A perspective in Critical Care argues that pneumonia-associated sepsis should be understood as a multidimensional syndrome driven by loss of ...
Genetic Testing Could Reshape Emergency Prescribing, but the Evidence Is Not There Yet
A new perspective argues that pharmacogenomic testing could improve emergency department prescribing, but no randomized controlled trials have yet tested ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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