Rare POLE p.T278K Mutation Drives Ultramutated Endometrial Cancer in Landmark Case
A detailed case report from China shows that a rare non-hotspot POLE p.T278K mutation, alongside dual MSH6 frameshift variants and ...
Tag: POLE
Hypermutation Gives Weak Cancer Drivers a Head Start, Study Finds
Mathematical modelling shows that elevated mutation rates and mutational biases, rather than altered selection, can explain why weak atypical KRAS ...
DNA Repair Gene Mutations Predict Dramatically Better Immunotherapy Outcomes in Colorectal Cancer
A study of 450 colorectal cancer patients shows that POLE and POLD1 proofreading gene mutations predict markedly better immunotherapy response ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!