Shared Genes, Opposing Effects: Hidden Genetic Link Between Heart Failure and Osteoporosis Revealed
A multi-omics study reveals that heart failure and osteoporosis share hundreds of genetic variants that often act in opposite directions, ...
Tag: pleiotropy
Hidden Genetic Threads Link Cancers Through Shared Regions and Pathways
A new PLOS Genetics study shows that shared genetic susceptibility across cancers is modest genome-wide but becomes structured and biologically ...
Why One Antibody Rules Them All: Epistasis Blocks Broad Flu Protection
Deep mutational scanning of the CR9114 antibody reveals that epistasis and pleiotropy make cross-reactive breadth against both influenza A and ...
Large Parkinson’s Study Confirms Rare ITSN1 Gene Variants Raise Disease Risk
An analysis of 8,660 genetically characterized Parkinson's patients from the ROPAD study confirms that heterozygous loss-of-function variants in the ITSN1 ...
Scientists Predict Super Peanut Crosses by Decoding Yield Gene Systems
Researchers mapped haplotype-based QTL-allele systems for peanut kernel and pod weight and predicted thirty optimal crosses that could push both ...
Genes Linked to Smoking May Shape Health Even in People Who Never Smoked
A study of older Americans finds that genetic scores for smoking predict worse health even among people who never smoked, ...
Scientists Find a Chromosome 5D Hotspot That Helps Wheat Sprout Under Drought
A multi-environment genome-wide association study of 389 wheat varieties has identified stable QTLs and candidate genes for drought tolerance during ...
New Family-Trio Genetic Method Exposes Hidden Bias in Causal Gene Studies
A new structural equation modeling framework called FT-SEM uses family trios and parental phenotypes to eliminate dynastic effects in GWAS ...
A Single Genetic Enhancer Helped Turn Wild Teosinte into High-Yielding Maize
Researchers identified a domestication-selected enhancer, Harvest Index 1, that helped raise maize harvest index by 81 percent compared with its ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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