Sevuparin 3 mg/kg dose selected in children with severe malaria
A phase I trial in 23 children with severe malaria selected 3 mg/kg per infusion as the maximum tolerated dose ...
Tag: Plasmodium falciparum
National PCR survey finds sub-microscopic malaria in 7% of microscopy-negative Ugandan children under five
A national cross-sectional study of Ugandan children under five found 7% of microscopy-negative samples positive by PCR, along with multiple ...
Where Malaria Could Return: Scientists Map the Riskiest Districts in a Malaria-Free Chinese City
By combining imported case records, mosquito habitat modeling and field surveillance, researchers have identified the Chongqing districts where malaria is ...
Rapid Malaria Test Shows High Sensitivity but Weak Specificity During Peak Transmission Season
A study of 511 participants in Nigeria found that a PfHRP2-based rapid diagnostic test detected most malaria infections during high ...
Malaria Parasite’s Odd Hsp90 Chaperone Proves Druggable in Yeast Screen
Researchers have shown that the malaria parasite's divergent second Hsp90 chaperone is functional, essential and selectively inhibited by the compound ...
Cell-Free Assay Cracks Open the Malaria Parasite’s Egress Machinery and Yields a Potent New Inhibitor
Researchers have reconstituted the malaria parasite's SERA6 egress protease maturation pathway in a cell-free assay, proving the mature enzyme is ...
Hidden Malaria in the Blood Bank: One in Seven Donors at Malawi’s Largest Transfusion Center Carries Silent Parasites
A study of 377 blood donors at Malawi's Lilongwe transfusion center found that 13.5 percent carried asymptomatic malaria parasites, dominated ...
Angiotensin II Blocks Malaria Parasite Invasion at Doses Below Blood Pressure Receptor Activation
A new in vitro study finds that angiotensin II inhibits Plasmodium falciparum invasion of red blood cells at a concentration ...
New Tools and Strategies Emerge as Global Malaria Control Faces Mounting Threats
A new Frontiers in Malaria editorial and its associated Research Topic detail how serological surveillance, transmission-blocking assays, modeling studies, and ...
Parasite Load Drives Malaria Symptoms in Children in Surprisingly Nonlinear Ways
The study's use of natural cubic splines deserves particular attention, because the choice of analytical method shapes what can be ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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