New AI Model Forecasts Hidden Side Effects of Drug Combinations
A new machine learning method called DCSE predicts side effects of drug combinations and introduces more realistic evaluation standards that ...
Tag: pharmacovigilance
Ravulizumab in Pregnancy Shows No New Safety Signals in Global Analysis
A global pharmacovigilance analysis of 354 pregnancies found no unexpected safety signals with the complement inhibitor ravulizumab, with outcomes consistent ...
Common Tuberculosis Drug Tied to Sharp Rise in Vision-Threatening Nerve Damage
A nationwide Korean cohort study of over 31,000 tuberculosis patients finds that the risk of optic neuropathy rises nearly sevenfold ...
Cameroon’s Drug-Resistant Tuberculosis Patients Fall Short of National Cure Targets, Major Review Finds
A new systematic review of fifteen studies finds that only 74.2 percent of drug-resistant tuberculosis patients in Cameroon achieve treatment ...
Aripiprazole Linked to Lower Hyponatremia Risk Than Olanzapine, Large Study Finds
A two-stage analysis combining FDA adverse event reports with Japanese claims data found aripiprazole associated with a significantly lower risk ...
Cancer Immunotherapy Side Effects Differ Sharply Across Racial Groups, Massive Data Analysis Reveals
An analysis of nearly half a million clinical trials and real-world data from over 91,000 patients reveals that immune-related side ...
Delamanid Proves Safe in Large Real-World Study of Drug-Resistant Tuberculosis in China
A 608-patient multicenter study in China found that delamanid-containing regimens for multidrug-resistant tuberculosis showed a safety profile consistent with clinical ...
Drug Safety Evidence Has a Shelf Life: Most Harm Findings Expire Within Three Years
A large retrospective cohort study of 505 meta-analyses finds that most early evidence on medication harms expires within about three ...
Common Antifungal Medicines in Pregnancy Linked to Altered Hormone Levels in Children
A Danish study of 589 mother–child pairs links azole antifungal use in pregnancy to altered adrenal hormone levels in infants, ...
Statistician Wins FDA Funding to Quantify Record Linkage Uncertainty in Real-World Evidence
A George Mason statistician has received FDA funding to develop regulatory-grade frameworks that quantify how record linkage errors affect the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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