FAERS analysis maps early, diverse ifosfamide neurological adverse events
A FAERS analysis of 786 ifosfamide-related neurological reports found a strong encephalopathy signal, a median onset of two days and ...
Tag: pharmacovigilance
Finerenone Safety Signals Identified in US and Japanese Reports
A dual-database pharmacovigilance analysis identified recurring renal and metabolic reporting signals for finerenone and flagged dizziness, abnormal liver-function results, increased ...
FDA-Approved RNA Drugs Show Mostly Mild Side Effects, But Long-Term Safety Data Remain Thin
A new cross-platform review of eighteen FDA-approved RNA therapeutics finds that adverse effects depend more on delivery chemistry and administration ...
Tocilizumab Rechallenge at Reduced Dose Still Triggers Fibrinogen Crash in Arthritis Patient
A case report shows tocilizumab-induced hypofibrinogenemia recurred in a rheumatoid arthritis patient even after the drug dose was substantially reduced.
Most Cancer Drug Side Effects May Not Be Preventable, Vietnamese Database Reveals
A year of pharmacovigilance reports from Ho Chi Minh City shows that of 253 confirmed adverse reactions to anticancer drugs, ...
FDA Database Study Flags Safety Signals for Widely Used HIV Drug Combination
One of the most widely prescribed HIV treatments in the world is now the subject of a large-scale safety review, ...
How a Four-Country Partnership Is Rewiring Drug Safety Oversight in Southern Africa
When a new medicine reaches the market, the work of protecting patients is only beginning. Before approval, clinical trials demonstrate ...
The skin as an early warning system: how drug rashes reveal systemic toxicity before lab tests
A comprehensive review argues that drug-induced skin phenotypes can act as early, bedside-visible risk signals of systemic toxicity, identifying specific ...
AI Model Reads Molecules Atom by Atom to Predict Dangerous Drug Combinations
A new multimodal transformer-CNN model called InfoMedex predicts 168 types of drug-drug interactions from molecular structure and uses atom-level attribution ...
Pharmacoepidemiology Reveals Hidden Safety Signals in New Antibiotics and Vaccines
A new editorial in Frontiers in Antibiotics highlights six pharmacoepidemiology studies that expose hidden safety signals in newer antibiotics, track ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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