New Framework Maps Complex Opioid Therapy Patterns in Health Data
A new methodological framework using Allen’s interval algebra and temporal margins improves the construction of opioid agonist therapy episodes in ...
Tag: pharmacovigilance
Ugandan Study Links Pharma Firm Size to Pharmacovigilance Reporting System Strength
A qualitative case study in Uganda found that the presence of pharmacovigilance systems appeared to be associated with pharmaceutical firm ...
U.S. PET Drug Adverse Events Remain Rare, Study Finds
A retrospective study of FDA adverse event reports from 2012 to 2024 finds that PET radiopharmaceuticals maintain a low risk ...
Early Resmetirom Safety Reports Show Hepatic and Biliary Signal Enrichment in FAERS
A study of postmarketing FAERS data found elevated liver and biliary reporting signals for resmetirom that partly attenuated against active ...
Analysis of 31,911 FAERS Reports Identifies Distinct Heart Toxicity Across Cancer Inhibitors
A 20-year retrospective pharmacovigilance study of FAERS data identified 31,911 reports of tyrosine kinase inhibitor cardiotoxicity characterized by class-specific adverse ...
Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase
A retrospective analysis of global pharmacovigilance data reveals significant safety signals for oxycodone abuse in the Americas and Western Pacific, ...
Systematic Review Maps Respiratory Safety Signals Across GLP-1 Receptor Agonists
A systematic review encompassing over one million patients evaluated respiratory safety signals associated with GLP-1 receptor agonists, finding common upper ...
FDA Database Study Differentiates Cutaneous Adverse Events for Liver Cancer Therapies
A disproportionality analysis of the FDA Adverse Event Reporting System reveals distinct cutaneous toxicity signals between immune checkpoint inhibitors and ...
Real-World Study Evaluates Intravenous Belimumab for Lupus in South Korea
A multicentre observational study in South Korea confirms the real-world safety and clinical effectiveness of intravenous belimumab in patients with ...
Systematic Review Analyzes Rare Modafinil-Associated Psychosis Across Published Clinical Reports
A systematic review of published case reports shows that modafinil exposure can trigger rare episodes of acute psychosis characterized by ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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