Pharmaceutical Chemistry

Physicians committee for responsible medicine efforts led to ISTAND program This week, the U.S. Food and Drug Administration (FDA) launched Innovative Science and Technology Approaches for New Drugs (ISTAND), a pilot program that will help…

Credit: TTUHSC The Lupus Research Alliance (LRA) recently named R. Bryan Sutton, Ph.D., a professor in the Department of Cell Physiology and Molecular Biophysics at the Texas Tech University Health Sciences Center (TTUHSC), as…

Credit: Chris Adam/Purdue University WEST LAFAYETTE, Ind. - During the COVID-19 pandemic, health care professionals and researchers have been confined mostly to using local and national datasets to study the impact of…

Two Dana-Farber studies selected for inclusion in the official ASH press program Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology (ASH) Annual Meeting on…

High-resolution mass spectrometry promotes new methods for analysis According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly…

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set Medicinal Chemistry for Pharmacy Students serves as a reference guide to pharmacists on aspects of…

In-body hospitals changes the futureCredit: 2020 Innovation Center of NanoMedicine Summary Open a new website summarized COINS's vision on one page in easy-to-understand manner. Introduce in-body hospitals aiming for realization in…

Glass tuning-fork-shaped tubing gives accurate, continuous measurements of drug dissolutionCredit: William Grover When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your…

Knowledge could guide development of sustainable production methods for plant-based medicinesCredit: From Flora De Filipinas by Francisco Manuel Blanco in U.S. public domain Palo Alto, CA-- Anthraquinones are a class of naturally…

The field of Advanced Therapy Medicinal Products research, which includes gene and cell therapies, is expected to grow exponentially in the coming years, with potentially up to 10-20 new drug applications submitted per year to the…

Rice scientists' atomic resolution protein models reveal new details about protein bindingCredit: Illustration by Mingchen Chen/Rice University HOUSTON - (Nov. 23, 2020) - Knowing precisely where proteins are frustrated could…

Credit: Zhao, S., Adamiak, J.W., Bonifay, V. et al. Defining new chemical space for drug penetration into Gram-negative bacteria. Nat Chem Biol 16, 1293-1302 (2020). https://doi.org/10.1038/s41589-020-00674-6... A collaborative…

Credit: The University of Queensland An experimental Alzheimer's disease treatment is proving effective at treating some of the most persistent, life-threatening antibiotic-resistant bacteria. Researchers from The University…

Credit: Adapted from Nano Letters 2020, DOI: 10.1021/acs.nanolet.0c03671 Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers…

UC scientist leads research to determine tolerance of HIV medications University of Cincinnati pharmaceutical sciences researcher Bingfang Yan, DVM, has received a $443,000 grant from the National Institutes of Health to study how common…

One-step multicomponent reaction with interpretable machine learning innovation to develop chemical library for drug discoveryCredit: Purdue University/Gaurav Chopra WEST LAFAYETTE, Ind. - Machine learning has been used widely in…

Credit: Universidad de Córdoba Nowadays, cannabidiol is a star component, not only in the world of cosmetics, but also in pharmaceutics and nutrition due to its antioxidant properties and its therapeutical potential. It is a natural…

'Survival of the fittest' phenomenon is only part of the evolution equationCredit: David S. Goodsell and RCSB PDB Darwin's theory of evolution should be expanded to include consideration of a DNA stability "energy code" - so-called…

Research in C. elegans shows how melatonin activates the BK channel in the brainCredit: Bojun Chen/UConn Health Melatonin is used as a dietary supplement to promote sleep and get over jet lag, but nobody really understands how it works…

Credit: 2020 Innovation Center of NanoMedicine Summary: Using practical nano-DDS technology, a polymeric nanomicelle that effectively delivers the potent mitotic inhibitor desacetyl vinblastine hydrazide (DAVBNH) to glioblastoma…