Pharmaceutical Chemistry

New Orleans, LA - A team of researchers from LSU Health New Orleans Neuroscience Center of Excellence and the University of Copenhagen provides the first evidence that patients with ocular hypertension may exhibit superior antioxidant…

This work, published in Cell and led by the UNC-Chapel Hill lab of Bryan L. Roth, MD, PhD, sets the stage for the discovery of new kinds of antidepressants, anti-anxiety drugs, and treatments for substance use disordersCredit: Roth Lab (UNC…

Researchers compared their developed carriers for delivery of genome editing (GE) tools with other available analogues.Credit: Peter the Great St.Petersburg Polytechnic University Researchers from Peter the Great St.Petersburg…

Sustainable processing delivers highest quality, minimizing odor and taste, says UC researcherCredit: University of Cincinnati A new study, co-led by University of Cincinnati researchers, describes the development of a refining process…

Credit: UPMC PITTSBURGH, Sept. 14, 2020 - University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause…

Unlike opioids, long-term cannabis use does not increase sensitivity to pain A recent study examining pain among cannabis users suggests that--unlike long-term opioid use--regular cannabis use does not appear to increase pain sensitivity.…

WEST LAFAYETTE, Ind. - Vancomycin-resistant enterococcus (VRE) is among the leading causes of hospital-acquired infections in the United States. An estimated 20,000 people in the U.S. become infected with it each year, and nearly 10% of…

Anti-inflammatory substances based on components of human cells could one day improve treatment in patients. Researchers at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed a method for producing…

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bio-active…

Fibroblast growth factor 1 effects on specific brain cell types, and on nets that enmesh neurons, inform how it restores blood sugar levels to normal in diabetic animalsCredit: Courtesy of KImberly Alonge/Schwartz Lab/UW Medicine Diabetes…

Cannabidiol (CBD) is an increasingly popular wellness trend. The compound, which occurs naturally in cannabis plants, is added to many products that claim to reduce anxiety, alleviate pain and more, without the intoxication of its cousin…

Novel Selenium-based compounds shown to have therapeutic potential Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease. Researchers from the…

University of Missouri scientists discover possible biological markers for identifying opioid use disorder.Credit: University of Missouri Scientists at the University of Missouri have discovered possible biological markers that…

Slow-release molecule featuring two complementary type 2 diabetes drugs controls blood sugar levels while promoting weight loss in mice for one week following a single injection DURHAM, N.C. - Biomedical engineers at Duke University have…

Nanomaterials show promise for treating hemophilia and cardiovascular disorder COLUMBUS, Ohio - Inserting genetic material into the body to treat diseases caused by gene mutations can work, scientists say - but getting those materials to…

A small molecule that activates the immune protein STING shows promising results against tumors in preclinical tests Scientists at Scripps Research have discovered a molecule that can activate a natural immune-boosting protein called…

A laboratory breakthrough in cell targeting may improve the safety of cancer-killing CAR T cellsCredit: UW Medicine Institute for Protein Design Scientists have demonstrated a new way to precisely target cells by distinguishing…

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system…

Credit: City College of New York The CUNY School of Medicine at The City College of New York and TechnoVax, Inc., a biotechnology developer of novel vaccines, announce a breakthrough in their collaborative effort to develop a…