Real-World Data Show Total Neoadjuvant Therapy Boosts Tumor Response in Rectal Cancer
A large real-world cohort from Thailand finds that total neoadjuvant therapy doubles pathological complete response rates in locally advanced rectal ...
Tag: pathological complete response
Mathematical Models Reveal How Shrinking Breast Tumors Move During Therapy
A study of 141 triple-negative breast cancer patients shows that advection terms in mathematical models best capture tumor cell movement ...
Immune Therapy Plus Chemotherapy Erases Stage IIIB Lung Tumor Before Surgery
A stage IIIB lung squamous cell carcinoma patient achieved a pathological complete response after neoadjuvant sugemalimab plus chemotherapy, with biomarker ...
Chemotherapy-Free Drug Combo Shows Promise for Early Triple-Negative Breast Cancer
A phase II trial found that neoadjuvant camrelizumab plus apatinib, a chemotherapy-free combination of immunotherapy and anti-angiogenic therapy, produced manageable ...
When Gastric Cancer Vanishes Before Surgery: New Study Maps Who Beats the Odds
A large Chinese multicenter study finds that 16.4 percent of locally advanced gastric cancer patients achieve a pathological complete response ...
Scientists Map a Hidden Malignant Program in Triple-Negative Breast Cancer
An integrated single-cell and spatial transcriptomic study has identified a triple-negative breast cancer-enriched malignant epithelial program, EP5, linked to aggressive ...
Biosimilar Trastuzumab EG12014 Matches Original Drug in Phase III Breast Cancer Trial
A Phase III trial of 807 patients found the trastuzumab biosimilar EG12014 statistically equivalent to reference trastuzumab in efficacy, safety, ...
Chemoradiotherapy May Unlock Immunotherapy in Hard-to-Treat Rectal Cancer
A new review argues that neoadjuvant chemoradiotherapy may induce immune checkpoint blockade responsiveness in mismatch repair-proficient rectal cancer, with sequential ...
Statisticians Flag Fragile Risk Model Behind Esophageal Cancer Survival Study
A new commentary warns that the three-factor risk model proposed for esophageal cancer patients achieving pathological complete response after neoadjuvant ...
Chemotherapy Before Surgery Spares Most Patients Radiation for HPV-Linked Throat Cancer
A multicentre Phase II trial found that neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil before transoral surgery allowed 91 percent ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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