Hidden Statistical Bias May Have Inflated Immunotherapy Hopes in Mesothelioma Trial
A new analysis shows that post-progression censoring may have generated a misleading survival advantage for nivolumab in second-line mesothelioma, resolving ...
Tag: overall survival
Biweekly Chemo Duo Shows Promise for Pancreatic Cancer Patients Over 75
A prospective Phase II trial in Japan found that biweekly gemcitabine plus nab-paclitaxel produced a 47.1 percent response rate and ...
Chemotherapy After Hormone Therapy Fails Leaves Metastatic Breast Cancer Patients With Grim Odds
A study of more than 5,000 US patients with HR-positive/HER2-negative metastatic breast cancer found median survival of only 13.5 months ...
Children With Down Syndrome Face 150-Fold Higher Leukemia Risk, and a Landmark Turkish Study Shows Why Getting the Diagnosis Right Saves Lives
A nationwide Turkish cohort study of 53 children with Down syndrome shows that those with Down syndrome-related myeloid leukemia achieved ...
Tumor Count and MELD Score Guide Surgery Choice for Intermediate Liver Cancer
A Taiwanese retrospective study shows that tumor number and MELD score can identify which intermediate-stage hepatocellular carcinoma patients benefit from ...
Lesser Lymph Node Surgery Matches Full Dissection for Node-Positive Breast Cancer Survival
A new study shows that targeted axillary dissection delivers equivalent recurrence, survival, and mortality outcomes compared with full axillary lymph ...
Liposomal Paclitaxel With HER-2 Blockers Shows Strong Real-World Results in Advanced Breast Cancer
A real-world study of 526 patients found that paclitaxel liposome combined with anti-HER-2 targeted therapies delivered median overall survival of ...
KRAS Mutation and Tumor Burden Power New Nomogram Defining Biologically Borderline Resectable Colorectal Liver Metastases
A Japanese multicenter study of 584 patients has developed a nomogram integrating KRAS mutation status, tumor burden score, nodal metastasis, ...
Bispecific Antibody Cadonilimab Shows Survival Edge Over PD-1 Drugs in Gastric Cancer
A network meta-analysis of eight Phase III trials involving 7,127 patients suggests that the PD-1/CTLA-4 bispecific antibody cadonilimab plus chemotherapy ...
Early Palliative Care Boosts Quality of Life and May Extend Survival in Cancer Patients
A meta-analysis of 39 randomized controlled trials involving 8,399 cancer patients found that early palliative care significantly improves quality of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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