Ion Channel Axis KCNE3-KCNQ1 Drives Bone Repair Through Vessel and Energy Metabolism Coupling
A mouse study finds that the KCNE3-KCNQ1 potassium channel axis couples mitochondrial energy metabolism to vessel growth and bone formation, ...
Tag: osteogenesis
Mushroom membranes sliced in different directions steer bone regrowth in rats
Slicing king oyster mushroom stipes lengthwise rather than crosswise preserves a naturally aligned hyphal network that guides bone-forming cells, blocks ...
Piezoelectric Hydrogel Turns Muscle Motion Into Signals That Rebuild Bone in Osteoporosis
A sandwich-structured PVDF and silk fibroin hydrogel laced with MXene converts everyday mechanical stress into electrical stimulation, tipping the bone-fat ...
Engineered Hydrogel Separates Strength From Bone-Building Biology
An architected polymer framework, bioactive glass and a soft hydrogel formed a composite that increased vascularized bone formation in rat ...
Sodium selenite curbs bone loss in mice through GPX4-linked ferroptosis inhibition
Sodium selenite reduced ferroptosis and improved bone formation through GPX4 in cell and ovariectomized mouse experiments, preclinical findings that do ...
Matrix origin determines how perlecan sugars steer stem cell fate
A laboratory study found that removing heparan sulfate chains from perlecan in cell-derived extracellular matrix altered human stem-cell differentiation according ...
Copine-derived peptides advance tissue repair through programmable biomaterials
A 2026 review finds that CPNE7-derived peptides can promote selected tissue-repair processes in preclinical models when engineered into collagen and ...
Low-concentration simvastatin boosts bone and vessel formation in preclinical tests
Cell-culture and mouse experiments found that low-concentration simvastatin promoted osteogenic activity and endothelial network formation through a process associated with ...
Aloe-emodin shows multi-target promise in mouse periodontitis models
Network analysis, mouse stem-cell assays and a murine periodontitis model indicate that aloe-emodin can suppress selected inflammatory signals while supporting ...
ACSS1 links nutrient stress to impaired bone formation in mouse models
A mouse study finds that nutrient stress elevates ACSS1 in bone-forming cells, impairing mitochondrial function and bone formation through increased ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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