Type II Collagen Scaffold Switches On a Genetic Circuit That Keeps Cartilage Young
A type II collagen–hyaluronic acid scaffold keeps chondrocytes in their healthy cartilage state for months and repairs full-thickness joint defects ...
Tag: osteoarthritis
Probiotic Vesicles Engineered to Home In on Cartilage Ease Osteoarthritis in Mice
Researchers engineered cartilage-targeting vesicles from the probiotic Lactobacillus rhamnosus GG that persist in joints, penetrate deep cartilage layers, and slow ...
Magnetic Pulses Rejuvenate Aging Cartilage by Switching On a Key Antioxidant Pathway
New research shows pulsed electromagnetic fields reduce senescence-driven cartilage degradation in aging mice by activating the Nrf2/HO-1 antioxidant pathway and ...
How Exercise Rejuvenates Aging Cartilage: Tiny Vesicles Carry a Longevity Signal
A new Nature Aging study shows that aerobic exercise enriches circulating extracellular vesicles with microRNA-29, which epigenetically reactivates the longevity ...
Brief Lift-Offs Keep Cartilage’s Hidden Fluid Cushion Alive, Study Finds
By pairing friction experiments with sample-specific computer models of human knee cartilage, researchers show that brief lift-off phases sustain the ...
Tiny RNA Fragment Emerges as Hidden Driver of Osteoarthritis Progression
Researchers report that the snoRNA-derived fragment sdRNA-D21 drives chondrocyte apoptosis in osteoarthritis by impairing BAG2-mediated ER-phagy and silencing DEPTOR, identifying ...
Antimalarial Drug Artemotil Shows Promise Against Cartilage Scarring in Osteoarthritis
New research shows the antimalarial derivative Artemotil suppresses STC1-driven TGF-beta/SMAD2/3 signalling to reduce fibrotic cartilage remodelling in osteoarthritis models.
Epigenetic Switch That Shields Cartilage From Osteoarthritis Is Revealed
A new study reveals that the epigenetic enzyme DOT1L protects cartilage in osteoarthritis by boosting ITCH expression, which in turn ...
AI Moves to Decode Pain: Machines Learn to See, Hear and Predict Suffering
A comprehensive review in the Journal of Translational Medicine maps how artificial intelligence is transforming pain assessment, imaging-based structural identification ...
MYDGF as a telomerase activator and therapeutic target for osteoarthritis
None Osteoarthritis remains one of the most prevalent chronic joint disorders worldwide, affecting hundreds of millions of people and representing ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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