Review Details Notch Pathway Role in Cancer Drug Resistance
A review in Discover Oncology details how Notch signaling pathways drive cancer drug resistance through mechanisms involving apoptosis, DNA repair, ...
Tag: oncology
Micropigmentation linked to improved body image in mastectomy survivors
A mixed-methods study in Supportive Care in Cancer found significant improvements in body image and quality of life among women ...
PET Scans Fall Short in Predicting Esophageal Cancer Immunotherapy Response
A prospective clinical trial found that standard 18F-FDG PET/CT metabolic parameters cannot reliably identify pathological complete responses in esophageal cancer ...
Molecular Sequencing Uncovers Rare Primary Breast Follicular Lymphoma Lacking BCL2 Rearrangements
Pathologists have documented the first next-generation sequencing profile of a primary breast follicular lymphoma lacking BCL2 rearrangements in a 55-year-old ...
Macrophage PD-L1 Loss Reduces CD80 Surface Expression
A new study in Frontiers in Oncology reveals that PD-L1 deletion or blockade in macrophages consistently reduces surface levels of ...
Pre-surgery drug combo cuts death risk in bladder cancer
A large international trial shows that combining immunotherapy and a targeted drug before surgery reduces the risk of death by ...
Metabolic Reprogramming Drives Therapeutic Resistance in Liver Cancer, Review Finds
Hepatocellular carcinoma represents a widespread and aggressive malignancy characterized by poor prognosis, where the emergence of therapeutic resistance continues to ...
AI Models Predict Head and Neck Cancer Outcomes from CT Scans
A new study demonstrates that foundation model-based multiple instance learning can predict clinical outcomes in head and neck squamous cell ...
Low MLH1 Methylation in Tunisian Colorectal Cancer Suggests Distinct Molecular Pathways
A retrospective study of 93 Tunisian colorectal cancer patients found that while MSI-H prevalence aligns with European rates, MLH1 promoter ...
Platelet to Lymphocyte Ratio Predicts Survival in Head and Neck Cancer Cohort
A retrospective cohort study found that an elevated pretreatment platelet-to-lymphocyte ratio independently associates with poorer overall and disease-specific survival in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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