HIF Ratio Predicts Head and Neck Cancer Invasiveness
A new study identifies the ratio of HIF-1α to HIF-2α as a key determinant of tumor satellite budding and invasive ...
Tag: oncology
SHMT2 Inhibition Sensitizes Renal Cancer Cells to Sorafenib
Inhibiting the enzyme SHMT2 reduces renal cell carcinoma proliferation and sensitizes cells to the drug sorafenib, suggesting a new therapeutic ...
Low Symptom Concordance Linked to Worse Quality of Life in Breast Cancer
A cross-sectional study finds that low concordance between patient and physician reporting of symptoms is associated with worse health-related quality ...
Pretreatment Serum Interleukin-10 Shows Potential Prognostic Link in Gastrointestinal Lymphoma
A retrospective cohort study found that higher pretreatment serum interleukin-10 was associated with overall survival in primary gastrointestinal lymphoma in ...
Mid-treatment MRI Predicts Pathologic Response in TNBC
A retrospective study of 517 patients found that mid-treatment MRI response strongly predicts pathologic complete response in triple-negative breast cancer, ...
Meta-analysis does not establish consistent survival advantage for early radical cystectomy in high-risk non-muscle-invasive bladder cancer
A systematic review of 18 studies, with 12 contributing to quantitative synthesis, does not establish a consistent survival advantage for ...
METTL16 Drives Lung Cancer Progression via GTSE1 Modification
A new study reveals that METTL16 accelerates lung adenocarcinoma progression by modifying GTSE1 via m6A, thereby regulating the p53 pathway ...
Colorectal Cancer Patients Prefer Hybrid Digital Health Support
A qualitative study in Supportive Care in Cancer finds that colorectal cancer patients prefer a hybrid system of information delivery ...
Nab-paclitaxel boosts residual cancer reduction in early breast cancer trial
A phase III trial in China found that dose-dense nab-paclitaxel significantly improved residual cancer burden rates compared to docetaxel in ...
Inhibiting Glucosylceramide Synthase Destroys Cancer Cells by Disrupting Lysosomal Function
Inhibiting glucosylceramide synthase with eliglustat promotes cancer cell death by impairing lysosomal degradation rather than accumulating ceramide.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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