Trapping rogue DNA rings in micronuclei could disarm aggressive tumors
An international research team has shown that rings of extrachromosomal DNA lose their cancer-driving activity when trapped in micronuclei, a ...
Tag: oncogenes
Silencing HPV16 Oncogenes E5 and E6 Emerges as a Promising Route Against Cervical Cancer
A new review in Virology Journal examines how siRNA and CRISPR/Cas gene-silencing technologies could target the HPV16 oncoproteins E5 and ...
Cancer’s Hidden Proteome: Thousands of Dark Proteins Emerge as Drug Targets
A landmark Perspective in Nature Reviews Cancer argues that the cancer dark proteome — thousands of uncharacterized proteins from non-canonical ...
Frozen but Faithful: Single-Cell Study Shows Cryopreserved Insulinoma Cells Keep Their Transcriptomic Identity
A multispecies single-cell RNA sequencing study shows that insulinoma cell lines from dogs, humans, rats and mice retain their transcriptomic ...
Seven Tiny RNAs Emerge as Potential Keys to Aggressive Lung Cancer Survival
A computational analysis of TCGA data has identified seven microRNAs that are both dysregulated in lung squamous cell carcinoma and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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