HeLa Cells Overcome EdU Toxicity via Stepwise Transcriptomic Desensitization
HeLa cells develop resistance to the thymidine analogue EdU by downregulating the SLC22A17 transporter and entering a state of transcriptomic ...
Tag: nucleotide excision repair
Circular RNA hsa_circ_0003472 Drives Pancreatic Cancer Growth and Gemcitabine Resistance
Researchers found that circular RNA hsa_circ_0003472 promotes pancreatic ductal adenocarcinoma progression and gemcitabine resistance by sponging microRNA-1253 to elevate ERCC1 ...
DNA lesions and repair-gene expression differ in bipolar disorder and sibling groups
A comparison of 127 participants found elevated oxidative DNA lesions and differing nucleotide-excision-repair gene expression in people with bipolar disorder ...
XPA confers ability of endonucleases to act processively and to incise damaged nucleosomal DNA
Repair of damaged DNA is a complex process, particularly when it is compacted into nucleosomes. There are a number of ...
DNA Repair Enzymes RecA and UvrD Emerge as Central Players in Antibiotic Persister Survival
New genetic analysis in Escherichia coli reveals that the DNA repair hub proteins RecA and UvrD are essential for fluoroquinolone ...
How Well Can Your Cells Fix Broken DNA? A Landmark Review Maps the Tools That Measure Nucleotide Excision Repair
A new critical review in Molecular Biology Reports systematically compares the biochemical, cellular, and genome-wide assays used to measure nucleotide ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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