Engineered Materials Offer New Framework for Controllable Cellular Immunotherapy
A review in Discover Oncology examines how engineered materials can address manufacturing, delivery, and safety bottlenecks across cellular immunotherapy.
Tag: non-viral delivery
Review Assesses Advances and Hurdles in Lipid Nanoparticle mRNA Cancer Therapies
A scientific review in Discover Nano highlights the therapeutic progress and ongoing translational hurdles facing lipid nanoparticle-mediated mRNA delivery systems ...
In Vivo Base Editing Treats Alpha-1 Antitrypsin Deficiency in Clinical Case
A clinical case study published in the Journal of Hepatology reports that in vivo base editing achieved precise SERPINA1 correction ...
OCT-guided laser and gold nanorods deliver opsin genes to degenerating retinas without viruses
Researchers report a non-viral, OCT-guided method using gold nanorods and a 980-nm laser to deliver the opsin MCO-020 to targeted ...
Peptide Analog Boosts Non-Viral CRISPR Delivery in Primary Human Skin Cells
Researchers engineered a cell-penetrating peptide, PF14-K, that delivers CRISPR ribonucleoproteins and DNA repair templates into primary human skin cells with ...
Densely Modified RNA Guides Push Prime Editing to Nearly 70% Efficiency in Living Mice
Scientists have engineered densely chemically modified guide RNAs that boost prime editing efficiency in the mouse liver to nearly 70 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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