Rigorous Testing Reveals Weak and Inconsistent Microbiome Signals in Lung Cancer Tumours
A rigorous multi-method study of lung cancer patients finds that tumour, tissue, and blood samples yield weak, inconsistent bacterial signals ...
Tag: non-small cell lung cancer
Tiny RNA Cluster Revealed as Master Switch Behind Lung Cancer Survival and Immune Evasion
Researchers at the University of Bern show that the miR105/767 microRNA cluster coordinates apoptosis, cell-cycle progression, and PD-L1 expression in ...
Drug Interactions and Side Effects Shape Safe Prescribing of Lung Cancer Pills
A comprehensive review maps how food, acid-reducing drugs and liver enzymes alter the exposure of thirty lung cancer targeted therapies, ...
Scientists Reverse Radiotherapy Resistance in Lung Cancer by Rewiring the Immune Microenvironment
New research shows that lung tumors become radioresistant through ATR signaling activation and immune suppression, but innate immune agonists and ...
Antibody-Drug Combination Falls Short in First-Line PD-L1-High Metastatic Lung Cancer Trial
The Phase 3 EVOKE-03/KEYNOTE-D46 trial found that sacituzumab govitecan plus pembrolizumab did not significantly improve progression-free or overall survival compared ...
New Molecular Glue Degrader TRI-611 Eliminates ALK-Driven Lung Cancer, Including in the Brain
Scientists report that TRI-611, a brain-penetrant molecular glue degrader, eliminates ALK fusion proteins and drives tumor regressions in preclinical models ...
Receptor Occupancy Fails to Predict Immune Activation in Pembrolizumab Dosing Study
A translational modelling study finds that PD-1 receptor occupancy does not predict immune activation during pembrolizumab therapy, challenging current dosing ...
Tree Gum Compounds Show Potent Anti-Cancer Power Against Lung Cancer Cells
Bioactive compounds from the medicinal tree Pistacia integerrima suppress the growth and migration of lung cancer cells by targeting PI3K, ...
ROS1 Fusion Subtype Shapes Survival in Advanced Lung Cancer, Real-World Data Show
A real-world study of 55 patients with advanced ROS1-rearranged non-small cell lung cancer shows that fusion subtype, PD-L1 expression and ...
Perioperative Immunotherapy More Than Doubles Event-Free Survival in Early-Stage Lung Cancer
Final Phase 3 IMpower030 results show that perioperative atezolizumab plus chemotherapy extended median event-free survival to 62.8 months versus 34.9 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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