The Brain’s Silent Partnership: How Astrocytes and Microglia Talk From Birth to Disease
A new review reveals that astrocytes and microglia engage in lifelong bidirectional communication that shapes brain development, maintains homeostasis, and ...
Tag: NF-kB signaling
Cholesterol Drug Fenofibrate Emerges as a Surprising Candidate Against Blinding Eye Disease
A comprehensive review finds that the lipid-lowering drug fenofibrate shows strong clinical evidence for slowing diabetic retinopathy and promising preclinical ...
Air Pollution’s Fingerprint in the Blood Reveals How Fine Particles May Drive Fatty Liver Disease
A UK Biobank study of over 52,000 adults identifies a 700-protein blood signature that statistically mediates the link between fine ...
Molecular Fingerprints Reshape the Fight Against Childhood Brain Tumors Above the Tentorium
A comprehensive new review explains how ZFTA and YAP1 gene fusions have redefined the diagnosis and treatment of pediatric supratentorial ...
Enzyme USP45 Drives Liver Cancer Growth by Stabilizing Oncoprotein CIAP2
Researchers in China have shown that the deubiquitinating enzyme USP45 promotes hepatocellular carcinoma progression by removing K48-linked ubiquitin chains from ...
Ancient Virus Hidden in Human DNA Engineered Into a Broad Cancer Vaccine Target
Scientists have engineered the envelope protein of human endogenous retrovirus-K to break immune tolerance and drive anti-tumor responses across multiple ...
Single-Cell Map Reveals Five Macrophage States Behind Chemotherapy Resistance in AML
Single-cell RNA sequencing of post-chemotherapy AML bone marrow has identified five macrophage polarization states whose abundance tracks with treatment response ...
Falling Levels of Immune Protein sCD30 in Spinal Fluid Track Huntington’s Disease Progression
A Swedish study confirms that the immune protein TNFRSF8 (sCD30) is halved in the cerebrospinal fluid of Huntington's disease gene ...
Ocean Microbes Yield Supercharged Enzymes Against Inflammation, Cancer, and Superbugs
A comprehensive review reveals that enzymes from marine microbes, hardened by extreme ocean conditions, show remarkable potential for treating chronic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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