Hedgehog coronaviruses converge on aminopeptidase N as their entry receptor
Hedgehog merbecoviruses use aminopeptidase N as a functional entry receptor through a structurally distinct APN-binding mode, revealing convergent evolution and ...
Tag: neutralizing antibodies
Breast milk-derived antibody preparation shields mice from influenza infection
A polyclonal secretory IgA preparation purified from pooled donor breast milk neutralized multiple respiratory viruses in vitro and reduced illness ...
Severe Hand, Foot and Mouth Disease Outbreak in Vietnam Traced to a Single Introduction of Enterovirus A71 Subgenogroup B5
A 2023 severe hand, foot and mouth disease outbreak in Vietnam was caused by a single introduction of enterovirus A71 ...
Antibodies Against Phage Fiber and Nozzle Proteins Undermine Acinetobacter Phage Therapy
New research shows that antibodies targeting the fiber and nozzle proteins of an Acinetobacter baumannii phage block infection and accelerate ...
Removing One Sugar Shield Makes Dengue Virus 2 More Visible to Potent Neutralizing Antibodies
A new cryo-EM and biophysical study shows that removing the N153 glycan from dengue virus 2 exposes previously hidden epitopes, ...
Decades-Old Smallpox Shots Leave Fading Immunity, With Chronic Illness Weakening the Shield
A large study of historically smallpox-vaccinated individuals finds residual but uneven immunity, with chronic disease and cancer linked to lower ...
Land Border Travelers in Ghana Show Sky-High COVID-19 Antibody Levels
A cross-sectional study of travelers entering Ghana through ten major land borders in 2022 found that over 92 percent carried ...
Engineered AAV Capsid Reaches the Outer Retina Through a Simple Eye Injection
Researchers used directed evolution to create AAV5-AlyT, an adeno-associated virus variant that delivers genes efficiently to photoreceptors after minimally invasive ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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