Trapping rogue DNA rings in micronuclei could disarm aggressive tumors
An international research team has shown that rings of extrachromosomal DNA lose their cancer-driving activity when trapped in micronuclei, a ...
Tag: neuroblastoma
Cancer’s Rogue DNA Can Backfire, Trapping Oncogenes in Micronuclei and Slowing Tumors
New research shows that damaged extrachromosomal DNA is trapped in transcriptionally silent micronuclei, impairing cancer cell fitness and predicting better ...
Nuclear Medicine Advances Span Prostate Cancer, Stroke, and Diabetes Imaging
New ahead-of-print studies in The Journal of Nuclear Medicine describe advances in prostate cancer theranostics, enzyme-enhanced tumor imaging, novel PET ...
Gene Signature Exposes Hidden Neuroblastoma Cells That Drive Poor Outcomes
St. Jude scientists and collaborators built a comprehensive single-cell dataset and patient-derived models to identify a malignant mesenchymal cell population ...
MRI Technique Reads Tumor Chemistry to Sort Risky Childhood Cancers Before Surgery
A Chinese research team shows that amide proton transfer MRI combined with machine learning can noninvasively distinguish high-risk from non-high-risk ...
Blocking a Single Protein Makes Childhood Cancer Cells Easier for Immunotherapy to Find
Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...
Tracer Debate: Fluorinated MIBG Alternative Sparks Scientific Exchange in Neuroblastoma Imaging
A scientific exchange in Pediatric Radiology over the merits of fluorinated MIBG PET imaging highlights the evidence still needed before ...
Rare Neurological Diseases in Children Are Rising Worldwide, First Global Analysis Finds
The first global assessment of rare neurological diseases in children finds rising prevalence and disability from 1990 to 2021, declining ...
Plant Alkaloid Narciclasine Shows Promise Against Aggressive Childhood Cancer in Lab Study
A new laboratory study shows that the Amaryllidaceae plant alkaloid narciclasine suppresses the proliferation, migration, and survival of neuroblastoma cells ...
New PET Scan Model Could Tell Dangerous Childhood Tumors From Benign Ones Without Surgery
A preliminary study shows that a multiparametric model combining ¹⁸F-MFBG PET/CT uptake measurements with clinical factors such as age and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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