Blood Test Could Replace Tumor Biopsies for Personalized Cancer Immunotherapy
A new study in Cancer Discovery shows that circulating tumor DNA and immune cells drawn from a simple blood sample ...
Tag: Neoantigens
Cancer’s Hidden Proteome: Thousands of Dark Proteins Emerge as Drug Targets
A landmark Perspective in Nature Reviews Cancer argues that the cancer dark proteome — thousands of uncharacterized proteins from non-canonical ...
Nanovaccine Built From Metal–Organic Frameworks Drives Tumours Into Full Retreat
A metal–organic framework nanovaccine co-delivering tumour antigens and STING agonists induced systemic tumour regression, immune memory and synergy with radiotherapy ...
HIV Blinds the Immune System to Lung Cancer Mutations, Study Suggests
A new analysis suggests HIV impairs the immune system's ability to recognize tumor neoantigens in non-small cell lung cancer without ...
Rethinking Cancer Vaccine Carriers: A Bottleneck-First Test of Antigen Delivery Platforms
A new review in Materials Today Bio proposes a bottleneck-first framework for evaluating antigen delivery platforms in therapeutic cancer vaccines, ...
Camouflaged Nanoparticles Could Rewrite the Rules of Cancer Vaccines
A new review details how nanoparticles disguised with red blood cell membranes, exosomes, and synthetic coatings, loaded with personalized neoantigens, ...
Immune system discovery linking inflammation to high blood pressure earns 2026 Joseph A. Vita Award
Vanderbilt scientist Dr. Annet Kirabo, whose research revealed how immune activation and inflammation drive hypertension, will receive the American Heart ...
Cancer Vaccines Enter a New Era as Personalized Immunotherapy Gains Momentum
A new review charts how mRNA, peptide, cell, and virus-based therapeutic vaccines, supercharged by AI-driven neoantigen prediction and combination immunotherapy, ...
mRNA Therapeutics Move Beyond Vaccines Into Cancer and Rare Disease Medicine
A new review details how mRNA therapeutics are expanding beyond infectious disease vaccines into cancer immunotherapy, protein replacement, autoimmune tolerance, ...
Dual T-Cell Activator Breathes New Life Into Checkpoint Therapy for Resistant Cancers
A selective dual T-cell activator directed at the TCR beta chain revives exhausted antitumor T cells and sensitizes checkpoint-resistant cancers ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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