Mathematical Models Reveal How Shrinking Breast Tumors Move During Therapy
A study of 141 triple-negative breast cancer patients shows that advection terms in mathematical models best capture tumor cell movement ...
Tag: neoadjuvant therapy
Immunotherapy Before Surgery: Sintilimab Helps Shrink Advanced Ovarian Cancer in Landmark Case
A case report describes advanced ovarian cancer shrinking dramatically after the PD-1 inhibitor sintilimab was added to chemotherapy, enabling complete ...
Immunotherapy After Surgery Shows Durable Results in High-Risk Esophageal Cancer
A phase II trial found that adjuvant sintilimab monotherapy after surgery met its primary efficacy endpoint with 87.5 percent one-year ...
Chemotherapy-Free Drug Combo Shows Promise for Early Triple-Negative Breast Cancer
A phase II trial found that neoadjuvant camrelizumab plus apatinib, a chemotherapy-free combination of immunotherapy and anti-angiogenic therapy, produced manageable ...
Breast Tumors Shed Their HER2 Target in More Than Half of Cases After Drug Therapy
A new MD Anderson study finds that 57 percent of residual breast tumors lose HER2 overexpression after HER2-targeted neoadjuvant therapy, ...
Immunotherapy, AI and an Aging Population Are Rewriting Esophageal Cancer Surgery
A sweeping 2024–2025 evidence review shows immune checkpoint inhibitors, frailty-adapted surgery, and artificial intelligence converging to transform esophageal cancer treatment ...
Biosimilar Trastuzumab EG12014 Matches Original Drug in Phase III Breast Cancer Trial
A Phase III trial of 807 patients found the trastuzumab biosimilar EG12014 statistically equivalent to reference trastuzumab in efficacy, safety, ...
MRI Signs and Blood Marker Reveal Which Pancreatic Cancer Patients Face Early Recurrence
Researchers in China have built a predictive model combining preoperative MRI features and serum CA19-9 levels that accurately identifies pancreatic ...
Stents Plus Neoadjuvant Therapy Reshapes Outcomes in Obstructive Colorectal Cancer
A multicenter retrospective study of 154 patients finds that combining self-expandable metal stents with modern neoadjuvant therapy reduces stomas and ...
Small Triple-Negative Breast Tumors Blur the Line Between Stage I and Stage II Treatment
A retrospective cohort study of 215 patients finds that small node-negative triple-negative breast cancers show similar biology and outcomes across ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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