Metabolic Enzyme NNMT Drives Ovarian Hormone Disorder Through Epigenetic Rewiring
New research in Nature Metabolism reveals that the metabolic enzyme NNMT drives hyperandrogenism in polyendocrine metabolic ovarian syndrome by depleting ...
Tag: Nature Metabolism
Bacterial Enzymes Reveal a Hidden NADPH Weakness in Aging Cells
A new Nature Metabolism study shows that NADH-reductive stress damages primary human cells mainly through NADPH depletion, and that a ...
Exercise Reshapes Thousands of Proteins Across Blood, Saliva and Urine, New Atlas Shows
A new Nature Metabolism study maps thousands of exercise-driven protein changes across blood, saliva and urine, and integrates tissue atlases, ...
Anti-ageing drug combo clears senescent cells and reverses liver scarring in first randomized trial
A phase-2 randomized trial shows intermittent dasatinib plus quercetin significantly improved liver fibrosis and resolved MASH in nearly half of ...
Microplastics Overwhelm Liver Immune Cells and Derail Metabolism in Mice
A twelve-week mouse study shows that microplastics and nanoplastics accumulate in liver macrophages and disrupt metabolism in strikingly different ways ...
How Ultraprocessed Foods Hijack Metabolism and the Brain
A randomized, controlled, crossover study in Nature Metabolism shows that ultraprocessed foods produce distinct acute metabolic responses that are correlated ...
Obesity leaves methylation marks in eggs that reprogram offspring metabolism
A Nature Metabolism study shows that maternal obesity leaves DNA methylation marks in oocytes at metabolic genes such as Hnf1α, ...
A single ubiquitin enzyme emerges as a master switch between liver repair and liver destruction in MASH
Researchers report that loss of the K63-linked ubiquitination enzyme UBE2N in hepatocytes drives metabolic dysfunction-associated steatohepatitis by blocking p62-mediated mitophagy ...
Urea cycle metabolite fuels leukemia growth by switching on a purine-recycling enzyme
A new Nature Metabolism study shows that BCR–ABL-driven leukemia cells hijack the urea cycle intermediate argininosuccinate to activate the nucleotidase ...
Six Experts Map the Future of Rare Metabolic Disease Research
Six leading researchers outline the opportunities, challenges and emerging priorities for advancing research and therapy development in rare metabolic diseases.
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!