A computational roadmap to activity-dependent myelination
A new perspective in Frontiers in Computational Neuroscience maps the emerging computational models of activity-dependent myelination, showing how oligodendrocytes tune ...
Tag: myelination
Human Brain Development May Set the Blueprint for Building Real AGI
A new hypothesis paper argues that the ordered stages of human neurodevelopment, from reflexes to physical grounding to social reasoning, ...
Master Switch Discovered That Decides How Adult Spinal Cord Stem Cells Choose Their Fate
New research reveals that the Hippo pathway effector YAP1 acts as a master switch controlling whether adult spinal cord stem ...
Timing Is Everything: Switching an Immune Switch On and Off Repairs Spinal Cord Injury in Mice
A new mouse study shows that activating the cGAS-STING immune pathway early after spinal cord injury and inhibiting it later ...
How Nerve Cells Measure Their Wires: Piezo1 Sets Myelin Length to Match Axon Size
A new PLOS Biology study shows that the mechanosensitive ion channel Piezo1 allows oligodendrocytes to sense axon diameter and locally ...
Faulty Epigenetic Switch Disrupts Brain Cell Cycles and Drives White Matter Defects in Autism-Linked Disorders
New research shows that pathogenic variants in the chromatin regulator MSL2 disrupt oligodendrocyte precursor cell division and myelination through loss ...
One Enzyme Emerges as Master Switch for Building Fast Peripheral Nerves
New research in zebrafish and mice identifies the cAMP-producing enzyme Adcy6 as an evolutionarily conserved master regulator that times Schwann ...
Oral Drug SUN11602 Speeds Early Nerve Regeneration in Rat Study
An experimental oral FGFR1 agonist called SUN11602 reduced inflammation, preserved nerve architecture and enhanced Schwann cell activity in the first ...
Piezo1 protein helps the brain measure nerve fibers to build myelin of the right length
Researchers at SUNY Upstate Medical University have identified the mechanosensitive protein Piezo1 as a key sensor that lets oligodendrocytes measure ...
White Matter Highways Linking the Brain’s Cortical Hierarchy May Explain Why Minds Differ
New research in Nature Human Behaviour shows that anatomical white matter tracts span the entire cortical hierarchy and that their ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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