Nitrate triggers oxidative stress and morphogenesis pathways in morel mushrooms, multi-omics study reveals
Nitrate and ammonium are the two principal forms of inorganic nitrogen that fungi encounter in soil, and most macrofungi show ...
Tag: multi-omics
Novel Ginseng-Derived Compound Shields the Liver From Acetaminophen Overdose by Damping HIF1α-Driven Glycolysis
A newly synthesized ginsenoside-lipoic acid hybrid called OCLA protected mice from acetaminophen-induced liver injury by directly targeting HIF1α and suppressing ...
Body Clock, Gut Microbes and DNA Methylation Converge in Depression Study
A pilot multi-omics study links disrupted sleep timing, specific gut microbial signatures, and altered DNA methylation at neural-related genes in ...
Givinostat blocks colorectal cancer growth by silencing ADAM12 through miR-1938
New research shows the HDAC inhibitor givinostat stalls colorectal cancer growth by upregulating miR-1938 to suppress ADAM12, with no systemic ...
Genetic Map of Brain and Blood Points to New Drug Targets for Neuropsychiatric Disorders
A Bayesian multi-omics analysis of GWAS and blood and brain QTL data has identified 86 gene-protein associations across nine neuropsychiatric ...
Climate-Ready Seaweeds: Pangenomics and Multi-Omics Could Rescue Kelp Forests
A new review outlines how pangenomics, seascape genomics, and multi-omics can be integrated into a single pipeline to breed climate-resilient ...
How the Aging Microbiome Shapes Health in Later Life
Microbial communities shift with age in ways that influence cardiometabolic health, cognition, immunity, and frailty, and BMC Geriatrics has launched ...
Melatonin Rewires Plant Metabolism to Survive Stress, Review Finds
A new review in Plant Cell Reports details how melatonin reprograms plant metabolism and coordinates hormone, ROS and nitric oxide ...
Hidden Immune Signal RSAD2 May Drive Endometrial Cancer Growth, Study Finds
A multi-omics study links the antiviral protein RSAD2 to CXCL1–CXCR1/2 signaling that recruits macrophages and drives endometrial cancer progression.
Wheat Seeds Show a Hormone Tipping Point Between Growth and Stress
A Chinese research team combined transcriptomics and metabolomics to reveal how wheat germinating seeds rewire their gene expression and metabolic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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