Angelman syndrome mice show disrupted Kv4.2 channel redistribution
A mouse study links loss of UBE3A to impaired Kv4.2–DPP6 complex remodeling and weakened dendritic channel gradients associated with excitability ...
Tag: mouse model
Quercetin reduces acute inflammatory and matrix-remodeling markers in mouse intracerebral hemorrhage
An experimental study found that quercetin reduced selected inflammatory and extracellular matrix-remodeling markers 24 hours after mouse intracerebral hemorrhage, while ...
Beer pretreatment reduced calcium oxalate crystal burden in mouse study; clinical stone series was descriptive
A controlled mouse study found that beer pretreatment was associated with less calcium oxalate crystal deposition, kidney injury and lower ...
Study of human datasets, Ang II-treated mice and cardiomyocytes links altered DRD1 to atrial fibrillation-related stress
A combined human-data, mouse and cell study found altered DRD1 expression in AF-associated tissues and a protective effect of DRD1 ...
Home-cage testing finds early memory deficits in Alzheimer’s mouse model
An automated home-cage platform detected working-memory deficits and subtle prefrontal synaptic changes in a familial Alzheimer’s disease mouse model at ...
Post-remission muscle loss in rheumatoid arthritis improved by dipyridamole in mice
In a mouse model of rheumatoid arthritis, dipyridamole improved persistent muscle loss and dysfunction after joint inflammation subsided, alongside restored ...
Aloe-emodin shows multi-target promise in mouse periodontitis models
Network analysis, mouse stem-cell assays and a murine periodontitis model indicate that aloe-emodin can suppress selected inflammatory signals while supporting ...
Time-series mouse study maps divergent diabetic reprogramming in kidney and heart
A six-point mouse RNA-sequencing study found that diabetic kidney tissue changed earlier than heart tissue, revealing a shift from early ...
Mechanical overload elicits weaker transcript isoform switching in aged mouse muscle
Mouse muscle subjected to mechanical overload showed extensive transcript isoform switching in adulthood, but the early response was attenuated in ...
Research report: Mitochondrial Genetic Background Shapes Baseline Retinal Function, Age‐Related Bioenergetic Remodeling, and Microglial STING Phenotypes
A mouse study found that inherited mitochondrial DNA variation was associated with age-dependent retinal respiratory-chain remodeling, mitochondrial DNA damage and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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