Humanized eNAMPT antibody reduces pain-related behavior in mice
A preclinical study found that the humanized eNAMPT-neutralizing antibody ALT-100 reduced pain-related behaviors and bone loss in a mouse model ...
Tag: monoclonal antibody
Sandwich ELISA Offers Rapid Antigen Test for Feline Coronavirus Detection
Researchers in China have developed a double-antibody sandwich ELISA that detects the feline coronavirus spike protein in faecal samples with ...
Gastric Cancer Drug Zolbetuximab Drives Widespread Albumin Loss in Real-World Patients
A real-world study finds that every patient treated with zolbetuximab for CLDN18.2-positive advanced gastric cancer developed hypoalbuminemia, with prior total ...
Ustekinumab Works Best in Crohn’s Disease Patients New to Biologics, Real-World Study Finds
A retrospective study of 61 Crohn's disease patients in China found that ustekinumab delivers stronger inflammatory control and endoscopic healing ...
Real-World Data Show Lecanemab Is Mostly Safe but Flag a Stroke Signal
A combined real-world cohort and FAERS analysis finds lecanemab generally safe in Alzheimer's patients but flags a strong, unlabeled signal ...
Nirsevimab Rollout Cuts Infant Bronchiolitis Across Europe, But Coverage Is Everything
A multinational analysis of 107,088 infant emergency visits across 12 European countries found that bronchiolitis reductions after nirsevimab introduction varied ...
Cholesterol-Lowering Antibody Evolocumab Cuts Heart Attack Risk in Landmark Analysis
A meta-analysis of nine randomised trials involving nearly 68,000 patients shows evolocumab dramatically lowers LDL cholesterol and reduces heart attacks ...
Monoclonal antibody AER002 fails to ease Long COVID symptoms in first randomized mechanistic trial
A randomized phase 2a trial found the SARS-CoV-2 monoclonal antibody AER002 safe but ineffective for Long COVID overall, though post-hoc ...
New Antibody Targets BAMBI to Rewire Immune Cells in Psoriatic Arthritis
Spanish researchers have developed a humanized monoclonal antibody, hB101.37, that inhibits the BAMBI pseudoreceptor and rebalances T cell immunity, showing ...
Adding an Antibody to Venetoclax Deepens Responses in Hard-to-Treat Lymphoma
A French retrospective study of 46 patients with relapsed or refractory Waldenström macroglobulinemia found that venetoclax combined with an anti-CD20 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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