FDA Approves Atezolizumab for Stage III dMMR Colon Cancer After Landmark ATOMIC Trial
The FDA has approved atezolizumab with chemotherapy for adjuvant treatment of stage III dMMR colon cancer after the phase III ...
Tag: microsatellite instability
Hidden Genetic Fault Lines Reshape Gastric Cancer Treatment Maps in Landmark Chinese Cohort
A 563-patient genomic study from Peking University reveals how KMT2C/D loss-of-function alterations define a hypermutated, MSI-high subgroup of gastric cancer ...
International Experts Set the Rules for Precision Testing in Bile Duct Cancer
An international expert consensus published in Clinical Cancer Bulletin establishes fifteen recommendations for molecular biomarker testing in intrahepatic cholangiocarcinoma, defining ...
AI Reads Routine Pathology Slides to Predict Cancer Biomarkers Across 12 Tumor Types
Researchers developed RIDGE, a weakly supervised deep learning system that predicts gene expression signatures and biomarkers such as microsatellite instability ...
DNA Repair Protein Fails to Explain Why a Common Dog Cancer Shrugs Off Chemotherapy Drug
New laboratory research shows that canine hemangiosarcoma cell lines resist the chemotherapy drug temozolomide through a mechanism independent of the ...
How Stomach Bacteria Rewire Immune Checkpoints to Fuel Gastric Cancer
A new review explains how Helicobacter pylori virulence factors drive PD-L1 expression in gastric cancer through crosstalk among the NF-κB, ...
Scientists Decode Colorectal Tumors With Imaging and Multi-Omics Fusion
A new review in the Journal of Translational Medicine maps how radiomics, pathomics and multi-omics integration can decode the tumor ...
Gene Amplifications, Not Mutation Load, Mark Poor Survival in Aggressive Bladder Cancer
A Swiss genomic study of muscle-invasive bladder cancer finds that oncogene amplifications, rather than tumor mutational burden or microsatellite instability, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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