Seven Tiny RNAs Emerge as Potential Keys to Aggressive Lung Cancer Survival
A computational analysis of TCGA data has identified seven microRNAs that are both dysregulated in lung squamous cell carcinoma and ...
Tag: microRNA
Macrophage Exosomes Carry a MicroRNA That Drives Scarring in the Lung, Study Finds
Researchers report that M2 macrophage-derived exosomal miR-350-5p accelerates pulmonary fibrosis by suppressing Smad7 and amplifying TGF-beta signaling in lung fibroblasts ...
Probiotic Vesicles Engineered to Home In on Cartilage Ease Osteoarthritis in Mice
Researchers engineered cartilage-targeting vesicles from the probiotic Lactobacillus rhamnosus GG that persist in joints, penetrate deep cartilage layers, and slow ...
RNA-Binding Protein Switch Could Sensitize Deadly Pancreatic Cancer to Radiation
Researchers in Beijing have identified a PUM2-PAFAH1B1 regulatory axis that triggers ferroptosis and overcomes radioresistance to iodine-125 seed therapy in ...
Gastric Cancer Study Retracted After Primer Mix-Up and HeLa Contamination Surface
A 2017 study linking miR-511 to TRIM24 regulation in gastric cancer has been retracted after investigators found that microRNA data ...
Tiny Genetic Regulators Go Awry in Rare DNA Repair Disorder, Study Finds
A new study reports that ATM-deficient ataxia-telangiectasia fibroblasts show reproducible depletion of the DNA damage response microRNAs miR-34a-5p and miR-26a-5p, ...
Tiny Genetic Switches May Help Explain Why Embryos Fail to Implant
A Korean case-control study finds that polymorphisms in miR-10a, miR-30c, miR-181a, and miR-499b, particularly in combination with PAI-1 genotypes, show ...
Methylmercury Rewires Brain Cell Genes at Doses That Leave Cells Alive
A new transcriptomic study reveals that non-lethal methylmercury exposure disrupts gene expression, microRNA regulation, and ion transport in rat neuronal ...
Tiny Blood RNAs Emerge as Early Warning Signals of Sepsis in Newborns
A validation study of 64 septic newborns finds that circulating microRNAs miR-15a, miR-132, and miR-223 are significantly dysregulated and may ...
New Database Reveals Hidden RNA Editing in Cancer’s Tiny Messengers
Researchers have launched EVmiRED, the first database cataloging microRNA editing events in tumor-derived extracellular vesicles, revealing that this hidden layer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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