MicroRNA miR-196a Clears Toxic Huntington’s Protein Clumps by Suppressing Rad23b
New research shows that the microRNA miR-196a clears toxic mutant huntingtin aggregates in Huntington's disease by suppressing Rad23b, a ubiquitin ...
Tag: microRNA
Heart Cells Have a 24-Hour Molecular Switch That Turns Sleep Apnea Damage On
A new study finds that intermittent hypoxia triggers a precise 24-hour threshold of microRNA remodeling in heart cells, with miR-146b-5p ...
One Tiny RNA, Many Cancers: Meta-Analysis Confirms miR-221 as a Pan-Cancer Killer Signal
A pan-cancer systematic review and meta-analysis links elevated microRNA-221 to significantly worse survival across multiple tumor types and maps its ...
Tiny RNA Molecule Triggers Explosive Cell Death in Aggressive Breast Cancer
Researchers have discovered that the microRNA miR-205-3p triggers inflammatory pyroptotic cell death in triple-negative breast cancer by repressing HSP90AB1, while ...
Pig Models Reveal MicroRNA Networks Driving Duchenne and Becker Muscular Dystrophy
Researchers mapped microRNA-messenger RNA regulatory networks in tailored pig models of Duchenne and Becker muscular dystrophy, identifying novel biomarker candidates ...
Lost Epigenetic Guardian CBX7 Emerges as Key Driver and Drug Target in Glioblastoma
A new review shows that the epigenetic regulator CBX7 acts as a tumor suppressor in glioblastoma, and that restoring its ...
Tiny RNA Molecule Pushes Schistosome Parasites Toward Self-Destruction
Researchers report that the microRNA sja-miR-2a-3p is enriched in reproductive tissues of Schistosoma japonicum and promotes apoptosis-related gene expression and ...
Hidden Antisense RNA May Fine-Tune a Stress Gene in Arabidopsis
A new study suggests that a natural antisense transcript overlapping the stress-responsive DOXC21-A gene in Arabidopsis may regulate its expression ...
Ferroptosis Genes Emerge as Potential Diagnostic Markers for Endometriosis
A bioinformatics study has identified six ferroptosis-related genes and three regulatory microRNAs that may serve as diagnostic biomarkers and therapeutic ...
Hidden messengers: matrix-bound vesicles rewrite the rules of tissue signalling
A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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