From Dish to Living Brain: How Lab-Grown Human Microglia Are Rewriting Neuroimmune Research
A new review charts how stem cell-derived human microglia, brain organoids and chimeric mice are overcoming the genetic and environmental ...
Tag: microglia
Alzheimer’s Risk Gene BIN1 Acts as a Brake on Brain Inflammation
New research shows that the Alzheimer's risk gene BIN1 acts as a brake on microglial inflammation, and its loss exaggerates ...
Cellular Nibbling: How Trogocytosis Shapes Immunity, Cancer, and Infection
A new review examines how trogocytosis, the process by which cells nibble membrane fragments from one another, shapes immune regulation, ...
Chemical Tags on Brain DNA Reveal How Alzheimer’s Risk Genes Do Their Damage
A large postmortem study identified 107 brain DNA methylation sites linked to Alzheimer's pathology and showed that methylation partially mediates ...
Brain Immune Cells Nibble Away Parkinson’s Protein Clumps to Shield Vulnerable Neurons
University of Oxford researchers have discovered that a specialised population of human microglia protects dopamine neurons in Parkinson's disease by ...
Nanoparticle Ferry Delivers Inflammation-Resolving Molecule to Spinal Cord to Rewire Pain at Its Source
Scientists have engineered an MG1 peptide-targeted liposome that delivers aspirin-triggered resolvin D1 to spinal microglia, reprogramming them via a newly ...
Timing Is Everything: Switching an Immune Switch On and Off Repairs Spinal Cord Injury in Mice
A new mouse study shows that activating the cGAS-STING immune pathway early after spinal cord injury and inhibiting it later ...
Hidden Brain Cells Called Oligodendrocytes Emerge as Unexpected Drivers of Parkinson’s Disease
A spatial multi-omics study in Nature Communications identifies disease-associated oligodendrocytes whose interleukin 33–ST2 signaling influences alpha-synuclein burden and motor symptoms ...
Dental Pulp Stem Cell Secretome Shows Promise for Stroke Recovery in Mice
A Chonnam National University study found that the human dental pulp stem cell secretome reduced oxidative stress and neuroinflammation while ...
Coffee Compound Trigonelline Eases Parkinson’s Symptoms in Mice by Calming Brain Inflammation and Reshaping Gut Microbes
A new preclinical study shows that trigonelline, a coffee-derived alkaloid, reduces alpha-synuclein pathology and neuroinflammation in Parkinson's model mice while ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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