Immune Cells Cluster, Not Crowd, in Melanoma That Spreads to the Brain
A Dutch study finds that melanoma brain metastases harbor far fewer but more tightly clustered immune cells than other metastases, ...
Tag: melanoma
Blood Vessel Protein Epac1 Found to Fuel Melanoma Growth Through YAP/TAZ Signalling
New research shows that the endothelial protein Epac1 drives melanoma growth and angiogenesis by coordinating VEGFR2 signalling, RhoA-dependent cytoskeletal dynamics, ...
Melanoma’s Genetic Blueprint Builds Immune-Proof Tumor Neighborhoods, Study Finds
Researchers at NYU Grossman School of Medicine show that loss of the NF1 tumor suppressor reorganizes melanoma tumors into immunosuppressive ...
Engineered NK Cells Target Hidden Cancer Antigen to Control Melanoma in Mice
Brazilian researchers engineered natural killer cells with a TCR-like CAR that recognizes an intracellular melanoma antigen displayed on HLA molecules, ...
ZIF-8 Nanocarrier Delivers Plant Drug and Gold Nanorods to Attack Melanoma
Researchers have built a ZIF-8-based nanosystem loaded with conferone and gold nanorods that shows potent, targeted, pH-responsive activity against melanoma ...
Simple Blood Test Shows Promise for Detecting Multiple Cancers in Horses
A new comparative study finds that serum thymidine kinase 1, measured with tritium-labeled thymidine, shows strong diagnostic accuracy for several ...
Interleukin-2 emerges as both engine and saboteur in tumor-infiltrating lymphocyte therapy
A new review details how interleukin-2 both powers and undermines tumor-infiltrating lymphocyte therapy, and how engineered alternatives may finally break ...
Gut Bacteria Sugar Turns Itself Into a Cancer Vaccine Supercharger
Scientists have transformed a sugar molecule produced by gut bacteria into a self-assembling nanovaccine that dramatically boosts antitumor immunity and ...
Engineered Herpes Viruses Show Modest but Meaningful Gains Against Solid Tumors
A meta-analysis of 38 clinical trials finds oncolytic herpes simplex virus therapy delivers modest anti-tumor activity across solid tumors, with ...
New Bispecific Antibody Redirects T Cells to Attack Melanoma Cells
Researchers at University Hospital Tübingen have engineered NG2-targeting bispecific antibodies that redirect T cells to kill melanoma cells, with a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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