Smart Shrinking Hydrogel Fights Infection and Rebuilds Wounds With a Flash of Light
A light-triggered contractile hydrogel that releases antibiotics on demand and then promotes blood vessel growth closed nearly 98 percent of ...
Tag: macrophage polarization
Ancient Herbal Formulas May Hold the Key to Unlocking Immunotherapy for Hard-to-Treat Colorectal Cancer
A new review proposes that standardized Traditional Chinese Medicine formulas could re-engineer the gut microbiome, myeloid cells, and tumor cell ...
Single-Cell Map Reveals Five Macrophage States Behind Chemotherapy Resistance in AML
Single-cell RNA sequencing of post-chemotherapy AML bone marrow has identified five macrophage polarization states whose abundance tracks with treatment response ...
Cell Study Reveals How TRIM28 Fires Up Inflammatory Macrophages to Drive Keratinocyte Overgrowth
New laboratory research shows that the protein TRIM28 drives macrophages toward a pro-inflammatory state through the NLRP3/SGT1 axis and SUMOylation, ...
Scientists Map the Cellular Drivers of Skin Aging and the Race to Reverse Them
A comprehensive new review details how senescent fibroblasts, macrophages, keratinocytes and stem cells drive skin aging through ROS, DNA damage, ...
Goldilocks Nerve Conduit Finds the Sweet Spot Between Guidance and Space
Researchers have identified an optimal 5 to 10 percent filling density for micropatterned nerve conduits that balances topographical guidance with ...
Muscle-Mimicking Conductive Hydrogel Offers New Hope for Pelvic Organ Prolapse Repair
Scientists have engineered an aligned, electrically conductive hydrogel that combines mechanical support with immune regulation to repair pelvic floor tissue ...
Smart Hydrogel Releases Drug Only Where Colitis Inflammation Runs Hot
Researchers have developed a reactive oxygen species-responsive hydrogel that shields berberine-loaded nanoparticles through the stomach and releases them only in ...
Ancient Chinese Herbal Formula Shows Promise Against Disc Degeneration
A classical Chinese herbal formula, Juanbi Tang, attenuates intervertebral disc degeneration in rats by suppressing p38MAPK/NF-κB signaling, activating Atg5-dependent autophagy, ...
Which Fat You Eat May Steer Immune Cells That Drive Liver Scarring
New research shows that individual fatty acid species differentially reprogram macrophage polarization and oxidative stress, indirectly modulating antioxidant signaling in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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